Article history: Received: 28-06-2017, Accepted: 01-12-2017, Published online: 29-12-2017
Corresponding author: Sudarshan Kumar
E-mail: email@example.comCitation: Mandhwani R, Bhardwaz A, Kumar S, Shivhare M, Aich R (2017) Insights into bovine endometritis with special reference to phytotherapy, Veterinary World, 10(12): 1529-1532.
Postpartum reproductive disorders cause heavy economic losses in dairy sector. Uterine infections include endometritis, metritis, mucometra, and pyometra. Postpartum endometritis in dairy cows has been defined as inflammation of endometrium occurring 21 days or more after parturition without systemic signs of illness. The treatment of endometritis with antimicrobials has met with varying degrees of success, inconsistent recovery rate, high cost of treatment, milk disposal, emergence of microbial resistance, and reduced phagocytic activity of polymorphonuclear leukocytes In our country, around 20,000 medicinal plant species have been recorded, but more than 500 traditional communities use about 800 plant species for curing different diseases. Many herbs such as garlic, neem, ashwagandha, and turmeric have been tried for the treatment of endometritis in cows with a good success.
Keywords: ashwagandha, bovine, endometritis, garlic, neem, phytotherapy, tulsi, turmeric.
2. Pillai, V.V. (2012) Efficacy of simultaneous use of enrofloxacin and metronidazole in the treatment of endometritis in crossbred cattle - a field trial. JIVA, 10(2): 37-39.
3. Gupte, A.G. and Deopurkar, R.L. (1993) Microbiological study of gynecological infection in cattle. Indian J. Anim. Reprod., 14: 118-119.
4. Kumar, A. (2013) Evaluation of Immunomodulatory and Therapeutic Efficacy of Turmeric, Neem and Garlic on Endometritisin Repeat Breeding Crossbred Cows. M.V.Sc. Thesis (Veterinary Gynaecology and Obstetrics), G.B. Pant University of Agriculture and Technology, Pantnagar.
5. Kamboj, V.P. (2000) Herbal medicine. Curr. Sci. Ind., 78(1): 35-39.
6. Galvao, K.N. (2012) Postpartum uterine diseases in dairy cows. Anim. Reprod. Sci., 9: 290-296.
7. Hansen, P.J. (1998) Regulation of uterine immune function by progesterone - Lessons from the sheep. J.Reprod.Immunol.,40: 63-70. [Crossref]
8. Williams, E.J., Fisher, D.P., England, G.C.W., Dobson, H., Pfeiffer, D.U. and Sheldon, I.M. (2005) Clinical evaluation of postpartum vaginal mucus reflects uterine bacterial infection and the inflammatory response to endometritis in cattle. Theriogenology, 63: 102-117. [Crossref] [PubMed]
9. Sheldon, I.M., Cronin, J., Goetze, L., Donorfio, G. and Schuberth, H.J. (2009) Defining postpartum uterine disease and the mechanisms of infection and immunity in the female reproductive tract in cattle. Reprod. Biol., 81: 1025-1032. [Crossref] [PubMed] [PMC]
10. Cengic, B., Varatanovic, N., Mutevelic, T., Katica, A., Mlaco, N. and Cutuk, A. (2012) Normal and abnormal uterine involution in cows monitored by ultrasound. Biotechnol. Anim. Husb., 28: 205-217. [Crossref]
12. Kumar, S. (2010) Computation of Judicious Treatment of Endometritisin Cows. Ph.D. Thesis (Animal Reproduction, Gynaecology and Obstetrics), Sher-e-Kashmir University of Agricultural Sciences and Technology, Jammu.
13. Ghasemi, F., Gonzalez-Cano, P., Griebel, P.J. and Palmer, C. (2012) Proinflammatory cytokine gene expression in endometrial cytobrush samples harvested from cattle with and without sub-clinical endometritis. Theriogenology, 78: 1538-1547. [Crossref] [PubMed]
14. Honparkhe, M., Ghuman, S.P.S., Singh, J., Dhindsa, S.S., Kumar, A., Chandra, M. and Brar, P.S. (2014). Diagnosing Sub-Clinical Endometritis Through Uterine Cytobrush Cytology and its Treatment with Proteolytic Enzymes in Buffaloes. In: 29th Annual Convention and National Symposium on Frontier Reproductive Biotechnologies for Enhancing Animal Fertility and Fecundity: Global perspective, 8-10, January 2014, Indian Society for Study of Animal Reproduction, Nagpur, Maharastra. pp 147.
15. Dhaliwal, G.S., Murray, R.D. and Woldehiwet, Z. (2001) Some aspects of immunology of the bovine uterus related to treatments for endometritis. Anim. Reprod. Sci.,67:135-152. [Crossref]
17. Sadanandan, B., Prerna, L., Humtsoe, H. and Mishra, A. (2014) Antibacterial activity of garlic against bacillus subtilis. Int. Rev. Appl. Biotechnol. Biochem., 2: 107-119.
18. Sarkar, P., Kumar, H., Rawat, M., Varshney, V.P., Goswami, T.K., Yadav, M.C. and Srivastava, S.K. (2006) Effect of administration of garlic extract and PGF2a on hormonal changes and recovery in endometritis cows. Asian. Aus. J. Anim., 19(7): 964-969. [Crossref]
19. Rahi, S. (2011) Immunotherapeutic Effect of Ashwagandha and Garlic on Endometritisin Repeat Bredding Cows. M.V.Sc Thesis (Veterinary Gynaecology and Obstetrics), G.B. Pant University of Agricultural Sciences and Technology, Pantnagar.
20. Devakumar, C. and Kumar, R. (2008) Total synthesis of Azadirachtin: A chemical odyssey. Curr. Sci. Ind., 95(5): 1-3.
21. Kumar, A., Gupta, H.P. and Prasad, S. (2013) Studies on the immunomodulatory and therapeutic efficacy of neem (Azadirachta indica) on endometritis in repeat breeding crossbred cows. Indian J. Anim. Reprod., 34(2): 1-5.
22. Gupta, S.K., Prakash, J. and Srivastava, S. (2002) Validation of traditional claim of Tulsi, Ocimum sanctum Linn as a medicinal plant. Indian J. Exp. Biol., 40: 765-773. [PubMed]
23. Bhatt, M.K., Shankar, M.B., Saluja, A.K., Dholwani, K.K. and Captain, A.D. (2012) Evaluation of antibacterial activity of Ocimum sanctum methanolic extract. J. Pharm. Sci. Innov, 1(4): 39-41.
24. Umadevi, M., Rajeswari, R., Sharmila, R.C., Selvavenkadesh, S., Pushpa, R., Sampath-Kumar, K.P. and Bhowmik, D. (2012) Traditional and medicinal use of Withania somnifera. Pharm.Innov., 1(9): 102-110.
25. Owis, M., Sharad, K.S., Shehbaz, A. and Saleemuddin, M. (2005) Antibacterial efficacy of Withania somnifera ashwagandha an indigenous medicinal plant against experimental murine salmonellosis. Phytomedicine, 12: 229-235. [Crossref] [PubMed]
26. Rathaur, P., Raja, W., Ramteke, P.W. and John, S.A. (2012) Turmeric: The golden spice of life.Int.J.Pharm.Sci. Res., 3(7): 1987-1994.
27. Rahi, S., Gupta, H.P., Prasad, S. and Baithalu, R.K. (2013) Phytotherapy for endometritis and subsequent conception rate in repeat breeding crossbreed cows. Indian J. Anim. Reprod, 34(1): 9-12.28. Singh, S. (2016) Phytotherapeutic Measures for Endometritis in Crossbred Cows. M.V.Sc. Thesis (Veterinary Gynaecology and Obstetrics). Nanaji Deshmukh Veterinary Science University, Jabalpur.