Article history: Received: 28-06-2017, Accepted: 11-08-2017, Published online: 12-09-2017
Corresponding author: Zuhair Bani Ismail
E-mail: firstname.lastname@example.orgCitation: Ismail ZB (2017) Mastitis vaccines in dairy cows: Recent developments and recommendations of application, Veterinary World, 10(9): 1057-1062.
The objective of this review article was to summarize the most recent clinical field trials that have been published evaluating the use of different types of vaccines against mastitis pathogens in dairy cows. Mastitis is one of the most common and economically important diseases in dairy cows in the world. The disease is considered an important welfare issue facing the dairy industry in addition to the loss of production and premature removal or death of affected cows. Losses are also related to high cost of veterinary medicines and the cost of unsalable milk of treated cows. Mastitis can be caused by either contagious or environmental pathogens both of which are best prevented rather than treated. In addition to the application of best management practices in the parlor during milking, vaccination against common udder pathogens is widely practiced in many dairy farms to prevent or reduce the severity of clinical mastitis. In this review, the most recent clinical field studies that evaluated the use of different types of vaccines in dairy cows are summarized.
Keywords: dairy cows, immunization, mastitis, pathogens, udder.
1. Nielsen, C., Ostergaard, S., Emanuelson, U., Andersson, H., Berglund, B. and Strandberg, E. (2010) Economic consequences of mastitis and withdrawal of milk with high somatic cell count in Swedish dairy herds. Animal, 4: 1758-1770. [Crossref] [PubMed]
3. Dobson, H., Walker, S.L., Morris, M.J., Routly, J.E. and Smith, R.F. (2008) Why is it getting more difficult to successfully artificially inseminate dairy cows? Animal, 2: 1104-1111. [Crossref] [PubMed] [PMC]
4. Unnerstad, H.E., Lindberg, A., Waller, K.P., Ekman, T., Artursson, K., Nilsson-Ost, M. and Bengtsson, B. (2009) Microbial etiology of acute clinical mastitis and agent-specific risk factors. Vet. Microbiol., 137: 90-97. [Crossref] [PubMed]
5. Persson, Y., Nyman, A.K. and Gronlund-Andersson, U. (2011) Etiology and antimicrobial susceptibility of udder pathogens from cases of subclinical mastitis in dairy cows in Sweden. Acta Vet. Scand., 53: 36. [Crossref] [PubMed] [PMC]
6. Schukken, Y.H., Bronzo, V., Locatelli, C., Pollera, C., Rota, N., Casula, A., Testa, F., Scaccabarozzi, L., March, R., Zalduendo, D., Guix, R. and Moroni, P. (2014) Efficacy of vaccination on Staphylococcus aureus and coagulase-negative Staphylococci intramammary infection dynamics in 2 dairy herds. J. Dairy Sci., 97: 5250-5264. [Crossref] [PubMed]
7. Barkema, H.W., Schukken, Y.H. and Zadoks, R.N. (2006) The role of cow, pathogen, and treatment regimen in the therpeutic success of bovine Staphylococcus aureus mastitis. J. Dairy Sci., 89: 1877-1895. [Crossref]
8. Perez, M.M., Prenafeta, A., Valle, J., Penades, J., Rota, C., Solano, C., Marco, J., Grillo, M.J., Lasa, I., Irache, J.M., Maira-Litran, T., Jimenez-Barbero, J., Costa, L., Pier, G.B., de Andres, D. and Amorenaa, B. (2009) Protection from Staphylococcus aureus mastitis associated with poly-N-acetyl β-1,6 glucosamine specific antibody production using biofilm-embedded bacteria. Vaccine, 27: 2379-2386. [Crossref] [PubMed] [PMC]
9. Pereira, U.P., Oliveira, D.G.S., Mesquita, L.R., Costa, G.M. and Pereira, L.J. (2011) Efficacy of Staphylococcus aureus vaccines for bovine mastitis: A systematic review. Vet. Microbiol., 148: 117-124. [Crossref]
11. Freick, M., Frank, Y., Steinert, K., Hamedy, A., Passarge, O. and Sobiraj, A. (2016) Mastitis vaccination using a commercial polyvalent vaccine or a herd-specific Staphylococcus aureus vaccine. Results of a controlled field trial on a dairy farm. Tierarztl. Prax., 4: 219-229. [Crossref] [PubMed]
12. Bradley, A.J., Breen, J.E., Payne, B., White, V. and Green, M.J. (2015) An investigation of the efficacy of a polyvalent mastitis vaccine using different vaccination regimens under field conditions in the United Kingdom. J. Dairy Sci., 98: 1706-1720. [Crossref]
14. Piepers, S., Prenafeta, A., Verbeke, J., de Visscher, A., March, R. and de Vliegher, S. (2016) Immune response after an experimental intramammary challenge with killed Staphylococcus aureus in cows and heifers vaccinated and not vaccinated with Startvac, a polyvalent mastitis vaccine. J. Dairy Sci., 100: 769-782. [Crossref] [PubMed]
16. Wilson, D.J., Mallard, B.A., Burton, J.L., Schukken, Y.H. and Grohn, Y.T. (2009) Association of Escherichia coli J5-specific serum antibody responses with clinical mastitis outcome for J5 vaccinate and control dairy cattle. Clin. Vaccine Immunol., 16: 209-217. [Crossref]
17. Chang, B.S., Moon, J.S., Kang, H.M., Kim, Y.I., Le, H.K., Kim, J.D., Lee, B.S., Koo, H.C. and Park, Y.H. (2008) Protective effects of recombinant Staphylococcal enterotoxin Type C mutant vaccine against experimental bovine infection by a strain of Staphylococcus aureus isolated from subclinical mastitis in dairy cattle. Vaccine, 26: 2081-2091. [Crossref] [PubMed]
18. Leitner, G., Yadlin, N., Lubashevsky, E., Ezra, E., Glickman, A., Chaffer, M., Winkler, M., Saran, A. and Trainin, Z. (2003) Development of a Staphylococcus aureus vaccine against mastitis in dairy cows. II. Field trial. Vet. Immunol. Immunopathol., 3-4: 153-158. [Crossref]
19. Czernomysy-Furowicz, D., Fijalkowski, K., Silecka, A., Karakulska, J., Nawrotek, P., Drozd, R., Ferlas, M., Borkowski, J. and Jankowiak, D. (2014) Herd-specific autovaccine and antibiotic treatment in elimination of Staphylococcus aureus mastitis in dairy cattle. Turk. J. Vet. Anim. Sci., 38: 1-5. [Crossref]
20. Magas, V., Slobodanka, V., Pavlovic, V., Velebit, B., Mirilovic, M., Maletic, M., Duric, M. and Svetkana, N. (2013) Effiency evaluation of a bivalent vaccine in the prophylaxis of mastitis in cows. Acta Vet. (Beograd), 63: 525-536. [Crossref]
21. Prenafeta, A., March, R., Foix, A., Casals, I. and Costa, L. (2010) Study of the humoral immunological response after vaccination with a Staphylococcus aureus biofilm-embedded bacterin in dairy cows: Possible role of the exopolysaccharide specific antibody production in the protection from Staphylococcus aureus induced mastitis. Vet. Immunol. Immunopathol., 134: 208-217. [Crossref]
22. Slobodanka, V., Pavlovic, M., Pavlovic, V. and Sonja, O. (2008) Immunoprophylaxis of Staphylococcus aureus mastitis in dairy cows. Acta. Vet. (Beograd), 58: 221-230. [Crossref]23. Lee, J.W., O'Brien, C.N., Guidry, A.J., Paape, M.J., Shafer-Weaver, K.A. and Zhao, X. (2005) Effect of a trivalent vaccine against Staphylococcus aureus mastitis lymphocyte subpopulations, antibody production, and neutrophil phagocytosis. Can. J. Vet. Res., 69: 11-18. [PubMed] [PMC]