Investigation of haptoglobin, serum amyloid A, and some biochemical parameters in calves with omphalitis

Vet World Vol.11 August-2018 Article-6

Research Article

Veterinary World, 11(8): 1055-1058

https://doi.org/10.14202/vetworld.2018.1055-1058

K. Bozukluhan¹, O. Merhan², M. Ogun², B. Kurt³, M. Cihan³, E. E. Erkilic⁴, G. Gokce⁴, U. Aydin³, and A. Ozcan⁵

1. Kars School of Higher Vocational Education, University of Kafkas, Kars, Turkey.
2. Department of Biochemistry, Faculty of Veterinary Medicine, University of Kafkas, Kars, Turkey.
3. Department of Surgery, Faculty of Veterinary Medicine, University of Kafkas, Kars, Turkey.
4. Department of Internal Medicine, Faculty of Veterinary Medicine, University of Kafkas, Kars, Turkey.
5. Department of Medical Biochemistry, Faculty of Medicine, University of Kafkas, Kars, Turkey.

Background and Aim: In this study, it was aimed to determine the concentration of some important acute phase proteins (APPs) and some biochemical parameters pre-operative and post-operative in calves with omphalitis.

Materials and Methods: A total of 20 calves were used in the study and they consist of 10 clinically healthy calves that were used as a control and 10 calves with omphalitis were used as the treatment group. Blood samples were collected from Vena jugularis of animals to tubes with anticoagulant (sodium citrate) and without anticoagulants, pre-operative (day 0), and post-operative (day 7). Samples were used to determine the concentration of haptoglobin (Hp), serum amyloid A (SAA), ceruloplasmin (Cp), fibrinogen, glucose, total protein, albumin, urea, total bilirubin, creatinine, calcium, phosphorus, aspartate aminotransferase (AST), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GGT) concentrations.

Results: While the Hp, SAA, Cp, fibrinogen, urea, creatinine, total bilirubin, ALP, and GGT concentrations were statistically and significantly increasing rather than the control group during the pre-operative period for calves with omphalitis, they decreased to the post-operative period. Moreover, an insignificant increase in the glucose, total protein, and AST concentrations and an insignificant decrease in the albumin, calcium, and phosphorus concentrations were statistically determined.

Conclusion: We have the opinion that the assessment of biochemical parameters and especially APP levels in calves with the omphalitis together with the clinical findings may be important in terms of the treatment and prognosis. Keywords: acute phase protein, biochemistry parameters, calves, omphalitis.

Keywords: acute phase protein, biochemistry parameters, calves, omphalitis.

How to cite this article: Bozukluhan K, Merhan O, Ogun M, Kurt B, Cihan M, Erkilic EE, Gokce G, Aydin U, Ozcan A (2018) Investigation of haptoglobin, serum amyloid A, and some biochemical parameters in calves with omphalitis, Veterinary World, 11(8):1055-1058.

Received: 31-03-2018 Accepted: 18-06-2018 Published online: 04-08-2018

Corresponding author: K. Bozukluhan E-mail: kbozukluhan@hotmail.com

DOI: 10.14202/vetworld.2018.1055-1058

Copyright: Bozukluhan, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.