Open Access
Research (Published online: 08-07-2018)
4. Effects of various surgical procedures on biochemical parameters of Nigerian dogs and their clinical implications
Aboh Iku Kisani, Terzungwe Tughgba and Abdullahi Teleh Elsa
Veterinary World, 11(7): 909-914

Aboh Iku Kisani: Department of Veterinary Surgery and Theriogenology, College of Veterinary Medicine, Federal University of Agriculture, P.M.B. 2373, Makurdi, Benue State, Nigeria.
Terzungwe Tughgba: Department of Veterinary Surgery and Theriogenology, College of Veterinary Medicine, Federal University of Agriculture, P.M.B. 2373, Makurdi, Benue State, Nigeria.
Abdullahi Teleh Elsa: Department of Veterinary Surgery and Theriogenology, College of Veterinary Medicine, Federal University of Agriculture, P.M.B. 2373, Makurdi, Benue State, Nigeria.

doi: 10.14202/vetworld.2018.909-914

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Article history: Received: 02-02-2018, Accepted: 21-05-2018, Published online: 08-07-2018

Corresponding author: Aboh Iku Kisani


Citation: Kisani AI, Tughgba T, Elsa AT (2018) Effects of various surgical procedures on biochemical parameters of Nigerian dogs and their clinical implications, Veterinary World, 11(7): 909-914.

Aim: The importance of physical and psychological stress caused by pain during surgery cannot be overemphasized. The aim of this study was to assess the effects of ovariohysterectomy (OVH), gastrotomy (GST), and intestinal resection and anastomosis (IRA) on biochemical parameters of Nigerian dogs anesthetized with the xylazine-propofol combination.

Materials and Methods: A total of 12 dogs were randomly divided into three groups of four each. The animals were treated with xylazine and propofol anesthetics for OVH, GST, and IRA in Groups 1-3, respectively. Blood samples were collected at 0 h, 2, 24, 48, 72, 96, 120, and 144 h postsurgery for determination of cortisol (CORT), glucose (GLU), total protein (TP), albumin (ALB), globulin (GL), and ALB/GL ratio.

Results: There were significant increases (p<0.05) in mean CORT concentrations 2 h postsurgery in the three groups and at 24 h in Group 3 and 96 h in Groups 1 and 3, respectively. GLU concentrations increased significantly (p<0.05) in the three groups at 2 h postsurgery. The mean protein concentrations in Groups 2 and 3 decreased significantly (p<0.05) at 2h and 24 h and 72 h, 96 h, 120 h, and 144 h in Group 3, respectively. There was significant decrease (p<0.05) in the mean ALB concentrations at 2 h, 24 h, 72 h, 96 h, 120 h, and 144 h postsurgery. There was a significant difference (p<0.05) in the mean GL concentrations in Group 3 at 24 h, 72 h, 96 h, and 144 h. All other parameters were not significantly different (p>0.05) in comparison with the control.

Conclusion: Xylazine-propofol combination could decrease humoral immune status and increase serum GLU level invariably portending a high risk of diabetes in the vulnerable dogs.

Keywords: anesthesia, cortisol, stress response, surgery.


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