Open Access
Research (Published online: 02-03-2018)
1. Modeling the potential risk factors of bovine viral diarrhea prevalence in Egypt using univariable and multivariable logistic regression analyses
Abdelfattah M. Selim, Mahmoud M. Elhaig, Sherif A. Moawed and Ehab El-Nahas
Veterinary World, 11(3): 259-267

Abdelfattah M. Selim: Department of Animal Medicine (Infectious Diseases), Faculty of Veterinary Medicine, Benha University, P.O. Box 13736, Toukh, Egypt.
Mahmoud M. Elhaig: Department of Animal Medicine (Infectious Diseases), Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt.
Sherif A. Moawed: Department of Animal Wealth Development, Biostatistics Division, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt.
Ehab El-Nahas: Department of Virology, Faculty of Veterinary Medicine, Benha University, P.O. Box 13736, Toukh, Egypt.

doi: 10.14202/vetworld.2018.259-267

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Article history: Received: 09-09-2017, Accepted: 29-01-2018, Published online: 02-03-2018

Corresponding author: Sherif A. Moawed


Citation: Selim AM, Elhaig MM, Moawed SA, El-Nahas E (2018) Modeling the potential risk factors of bovine viral diarrhea prevalence in Egypt using univariable and multivariable logistic regression analyses, Veterinary World, 11(3): 259-267.

Aim: The present cross-sectional study was conducted to determine the seroprevalence and potential risk factors associated with Bovine viral diarrhea virus (BVDV) disease in cattle and buffaloes in Egypt, to model the potential risk factors associated with the disease using logistic regression (LR) models, and to fit the best predictive model for the current data.

Materials and Methods: A total of 740 blood samples were collected within November 2012-March 2013 from animals aged between 6 months and 3 years. The potential risk factors studied were species, age, sex, and herd location. All serum samples were examined with indirect ELIZA test for antibody detection. Data were analyzed with different statistical approaches such as Chi-square test, odds ratios (OR), univariable, and multivariable LR models.

Results: Results revealed a non-significant association between being seropositive with BVDV and all risk factors, except for species of animal. Seroprevalence percentages were 40% and 23% for cattle and buffaloes, respectively. OR for all categories were close to one with the highest OR for cattle relative to buffaloes, which was 2.237. Likelihood ratio tests showed a significant drop of the -2LL from univariable LR to multivariable LR models.

Conclusion: There was an evidence of high seroprevalence of BVDV among cattle as compared with buffaloes with the possibility of infection in different age groups of animals. In addition, multivariable LR model was proved to provide more information for association and prediction purposes relative to univariable LR models and Chi-square tests if we have more than one predictor.

Keywords: bovine viral diarrhea, likelihood ratio test, logistic regression, odds ratio, seroprevalence.


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