Vet World Vol.12 October-2019 Article-19
Research Article
Veterinary World, 12(10): 1650-1656
https://doi.org/10.14202/vetworld.2019.1650-1656
Histological assessment of the efficiency of rabbit serum in healing skin wounds
2. Department of Anatomy and Histology, College of Veterinary Medicine, University of Baghdad, Baghdad, Iraq.
Background and Aim: This study aimed to investigate the impact of rabbit serum on skin wound healing with the help of histological examination.
Materials and Methods: A total of ten indigenous rabbits were used in this study. The animals were divided into two groups: control and serum- treated. The histological assessment was done with a paraffin embedding technique and the histological sections were stained with H&E stain.
Results: Severe infiltration of polymorphonuclear leukocytes with severe fibrin deposits were seen in serum treated group at 2 days post-injury; at 7 days post-injury the changes revealed moderate fibroplasia, fibrin deposit and severe infiltration of both mononuclear and polymorphonuclear leukocytes; at 14 days post-injury, there were marked epithelization and dermal deposition of collagen fibers; and at 21 days post-injury, the epidermis completed epithelization and the dermis showed neither fibroplasia nor infiltration of mononuclear and polymorphonuclear leukocytes.
Conclusion: The results indicated that rabbit's serum can prevent wound infection, accelerate epithelialization and cutaneous regeneration with less granulation. Keywords: healing, rabbits, serum, skin, wounds.
Keywords: healing, rabbits, serum, skin, wounds.
How to cite this article: Majeed AA, Abood DA (2019) Histological assessment of the efficiency of rabbit serum in healing skin wounds, Veterinary World, 12(10): 1650-1656.
Received: 30-04-2019 Accepted: 06-09-2019 Published online: 28-10-2019
Corresponding author: Abeer Ahmed Majeed E-mail: sabahali503@yahoo.com
DOI: 10.14202/vetworld.2019.1650-1656
Copyright: Majeed and Abood, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.