Veterinary World, Vol.2(6): 215-216 RESEARCH
Study
of Antiulcer Activity of Bauhinia racemosa Lam in rats
V.I.Borikar,
C.R Jangde, Preety Philip and D.S. Rekhe
Department
of Veterinary Pharmacology and Toxicology,
Nagpur
Veterinary College, M.A.F.S.U. Nagpur
(440006) Maharashtra
Corresponding
author email : dr_vet08@rediffmail.com
Abstract
An experiment was conducted to study the antiulcer
effect of the dried fruit powder of the plant Bauhinia racemosa in
Wistar albino rats. Thirty Wistar
rats of either sex weighing between 150 - 200gm were selected and divided into
five groups, each comprising of six rats. The rats were divided into 5 groups T1 T2, T3, T4, and T5 and were given 0.5 ml normal saline,
aqueous extract in the dose rate of100mg/kg body weight, 200mg/kg body weight,
alcoholic extract @100mg/kg body weight and 200mg/kg body weight respectively.
After one hour all the groups were administered Paracetamol at a dose rate of
200mg/kg body weight orally. After 24hrs, the number of ulcers, ulcer score,
percent incidence, ulcer index and healing index were recorded. From the
results obtained it was concluded that aqueous extract in the dose rate of
200mg/kg body weight and alcoholic extract (100mg/kg & 200mg/kg body
weight) could produce antiulcer activity.
Keywords: Bauhinia racemosa, Paracetamol, antiulcer activity