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Open Access
Copyright: The authors. This article is an open access
article licensed under the terms of the Creative Commons Attribution License
(http://creativecommons.org/licenses/by/2.0) which permits unrestricted use,
distribution and reproduction in any medium, provided the work is properly
cited.
Review (Published
online : 08-09-2013)
24. Crimean-Congo hemorrhagic fever: a comprehensive review - Aman
Kamboj and Himanshu Pathak
Veterinary World, 6(10): 812-817
doi:
10.14202/vetworld.2013.812-817
Abstract
Crimean-Congo Hemorrhagic Fever (CCHF)
is an emerging tick-born zoonotic disease in India which is caused
by Nairovirus of Bunyaviridae family. CCHF is reported from about
30 countries of the world. An outbreak of CCHF has been reported
two years back in Gujarat which killed four people including two
physicians, one nurse and a rural housewife. Tick bite, contact
with infected material and nosocomial routes are the main routes
of infection. This disease is not much important in animals as
animals are asymptomatic but domestic livestock play a vital role
in the transmission of disease to humans. So the persons
associated with animals like veterinarians, farmers and slaughter
house workers are also at the high risk of getting the infection.
The disease has a great public health importance. Rapid diagnosis
of disease is very important. The advent of molecular techniques
including real-time PCR allow the rapid diagnosis of CCHF. There
are limited treatment options for CCHF. Ribavirin is the only
known drug which is effective against CCHF.
Keywords: biosafety, Crimean-Congo hemorrhagic fever,
nosocomial, zoonotic disease
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