Postmortem detection and histopathological features of canine spirocercosis-induced putative esophageal chondrosarcoma

Vet World Vol.11 October-2018 Article-3

Research Article

Veterinary World, 11(10): 1376-1379

https://doi.org/10.14202/vetworld.2018.1376-1379

H. M. Suranji Wijekoon¹, D. M. S. Munasinghe², K. A. N. Wijayawardhane³, H. M. H. S. Ariyarathna³, Neil Horadagoda⁴, Jayanthe Rajapakse¹, and D. D. Niranjala De Silva³

1. Department of Veterinary Pathobiology, Division of Parasitology, Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Sri Lanka.
2. Department of Veterinary Clinical Sciences, Veterinary Teaching Hospital, Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Sri Lanka.
3. Department of Basic Veterinary Sciences, Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Sri Lanka.
4. University Veterinary Teaching Hospital Camden, University of Sydney, 410 Werombi Road, Camden, NSW 2570, Australia.

Background and Aim: The objective of this study was to describe and characterize the postmortem and histopathological findings of putative esophageal chondrosarcoma associated with Spirocerca lupi.

Materials and Methods: Spirocerca-associated esophageal nodules were collected from 54 dogs at postmortem examination and were stained with hematoxylin and eosin. Of the cases examined, 15 were selected randomly for further investigation, of which 11 were classified as non-neoplastic nodules while 4 had changes reflecting a neoplastic process.

Results: In all four neoplastic cases, the wall of the esophageal nodules contained islands and nests of highly proliferative atypical chondroblasts within a cartilaginous matrix. However, there was no statistically significant association between gender (p=0.228), age (p=0.568), and breeds (p>0.05) with the occurrence of spirocercosis. Moreover, all esophageal nodules identified were located near the caudal segment, and their diameters ranged from 1 to 6 cm (4.7±1.5 cm). A number of worms in each nodule varied from 5 to 25 (11.3±5).

Conclusion: Histopathology and cytology revealed that the wall of the esophageal nodules contained islands and nests of highly proliferative atypical chondroblasts within a cartilaginous matrix, a rare finding, and clinical challenge in spirocercosis. Keywords: chondrosarcoma, dog, esophagus, histopathology, Spirocerca lupi, spirocercosis.

Keywords: chondrosarcoma, dog, esophagus, histopathology, Spirocerca lupi, spirocercosis.

How to cite this article: Wijekoon HMS, Munasinghe DMS, Wijayawardhane KAN, Ariyarathna HMHS, Horadagoda N, Rajapakse J, De Silva DDN (2018) Postmortem detection and histopathological features of canine spirocercosis-induced putative esophageal chondrosarcoma, Veterinary World, 11(10): 1376-1379.

Received: 26-05-2018 Accepted: 27-08-2018 Published online: 03-10-2018

Corresponding author: H. M. Suranji Wijekoon E-mail: suranjisk@gmail.com

DOI: 10.14202/vetworld.2018.1376-1379

Copyright: Wijekoon HMS, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.