Antimicrobial susceptibility profiles of Staphylococcus spp. contaminating raw goat milk

Vet World Vol.14 May-2021 Article-3

Research Article

Veterinary World, 14(5): 1074-1079

https://doi.org/10.14202/vetworld.2021.1074-1079

Abimael E. Silva Júnior¹, Priscylla C. Vasconcelos¹, Mauro M. S. Saraiva¹, Lauro Santos Filho², Núbia M. V. Silva¹, Patricia E. N. Givisiez¹, and Celso J. B. Oliveira¹

1. Department of Animal Science, College for Agricultural Sciences, Federal University of Paraiba, Brazil.
2. Department of Pharmaceutical Sciences, College of Health Sciences, Federal University of Paraiba, Brazil.

Background and Aim: Antimicrobial resistance poses a major threat to global public health. Foodstuff of animal origin can serve as potential vehicles for the dissemination of antimicrobial-resistant bacteria and resistance genes to consumers. In view of the lack of knowledge about antimicrobial resistance in bacteria associated with goat milk, the aim of this study was to report species-level identification and antimicrobial susceptibility profiles of a large collection of Staphylococcus spp. isolates recovered from raw goat milk in Brazil.

Materials and Methods: A total of 434 Staphylococcus spp. isolates originated from 510 goat milk samples in Northeast Brazil were investigated. The isolates were obtained by conventional microbiological methods. Species identification and antimicrobial susceptibility testing were performed by means of a semi-automated system using a panel for biochemical tests and broth microdilution method for 19 antimicrobial drugs.

Results: Although Staphylococcus aureus (22.6%) accounted for the majority of the isolates, a total of 13 different non-aureus staphylococci spp. were identified. High resistance rates against erythromycin (40.8%), and the beta-lactams ampicillin (45.9%) and penicillin (42.9%) were observed among S. aureus isolates. The most significant findings were related to the resistance against quinupristin-dalfopristin, a drug of last resort used in human medicine to treat infections caused by vancomycin-resistant S. aureus and enterococci.

Conclusion: The high diversity of Staphylococcus spp. showing phenotypic resistance against different antimicrobial drugs encourages further investigations on the real impact of these bacteria as reservoirs of antimicrobial resistance genes to consumers. Furthermore, the potential impact of technological processes, such as pasteurization, fermentation, and maturation, on the maintenance and dissemination of antimicrobial resistance among the microbial populations in milk and dairy products must also be investigated. Keywords: antimicrobial resistance, dairy goats, food safety, Staphylococcus.

Keywords: antimicrobial resistance, dairy goats, food safety, Staphylococcus.

How to cite this article: Silva Júnior AE, Vasconcelos PC, Saraiva MMS, Santos Filho L, Silva NMV, Givisiez PEN, Oliveira CJB (2021) Antimicrobial susceptibility profiles of Staphylococcus spp. contaminating raw goat milk, Veterinary World, 14(5): 1074-1079.

Received: 08-07-2020 Accepted: 17-03-2021 Published online: 05-05-2021

Corresponding author: Celso J. B. Oliveira E-mail: celso.oliveira@academico.ufpb.br

DOI: 10.14202/vetworld.2021.1074-1079

Copyright: Silva Júnior, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.