Vet World Vol.16 August-2023 Article-12
Research Article
Veterinary World, 16(8): 1667-1672
https://doi.org/10.14202/vetworld.2023.1667-1672
Comparison of the efficacy of altrenogest versus transdermal progestin patches on estrus synchronization and ovulation in mares
2. Clinic for Obstetrics and Gynecology Andrology and Artificial Insemination of Domestic Animals, Faculty of Veterinary Medicine, Mahanakorn University of Technology, Bangkok, 10530, Thailand.
Background and Aim: The adhesive progestin patch was investigated for estrus synchronization in mares because this method is convenient and safe in other species. This study aimed to compare the efficacy of a transdermal progestin patch versus oral altrenogest on estrus synchronization, preovulatory follicle development, and ovulation.
Materials and Methods: Twenty-four broodmares were randomly divided into two groups. In Group 1, mares (n = 12) were fed 0.044 mg/kg altrenogest daily for 14 days. Group 2 (n = 12) mares were treated with adhesive transdermal progestin patches for 14 days. Mares were observed for estrus daily, from day 3 until day 7, after hormone withdrawal. Follicular development was determined by ultrasonography. The preovulatory follicle size and ovulation time after hormone treatments and ovulation rate were determined for both groups. Plasma progesterone levels were measured during the experimental periods and 2 days after hormone termination in both groups.
Results: The results revealed that the transdermal progestin patch efficiently controlled follicular growth and estrus synchronization in mares. The percentage of mares exhibiting estrus was similar in the altrenogest (100.00%) and transdermal patch (91.67%) groups. Ovulation rates were equivalent with either altrenogest or progestin patch protocols (91.67% [11/12] vs. 83.33% [10/12]). In addition, the preovulatory follicle size was similar in mares treated with altrenogest and progestin patches.
Conclusion: This study revealed that the transdermal progestin patch provides effective estrus synchronization and ovulation, similar to altrenogest treatment. However, the transdermal patch was more convenient with a shorter predictable ovulation time after estrus synchronization and should be considered as an alternative method for mares. Keywords: altrenogest, estrus synchronization, mare, progestin, transdermal patch.
Keywords: altrenogest, estrus synchronization, mare, progestin, transdermal patch.
How to cite this article: Kajaysri J and Wutthiwitthayaphong S (2023) Comparison of the efficacy of altrenogest versus transdermal progestin patches on estrus synchronization and ovulation in mares, Veterinary World, 16(8): 1667-1672.
Received: 21-04-2023 Accepted: 18-07-2023 Published online: 19-08-2023
Corresponding author: Jatuporn Kajaysri E-mail: jatuporn.kaj@cra.ac.th
DOI: 10.14202/vetworld.2023.1667-1672
Copyright: Kajaysri J and Wutthiwitthayaphong, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.