Open Access
Research (Published online: 15-02-2024)
13. Influence of idiopathic epilepsy on blood pressure and electrocardiography in dogs treated with phenobarbital
Yolanda Paim Arruda Trevisan, Maria Sabrina de Freitas, Maria Natalia de Freitas, Jaqueline Konrad, Juliano Bortolini, Ana Carolina Schipiura, Ana Flávia Borges de Freitas, Sarah Szimanski Pazzini, Arleana do Bom Parto Ferreira de Almeida, and Valéria Régia Franco Sousa
Veterinary World, 17(2): 356-360

Yolanda Paim Arruda Trevisan: Department of Internal Medicine for Small Animals at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil.
Maria Sabrina de Freitas: Department of Internal Medicine for Small Animals at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil.
Maria Natalia de Freitas: Department of Internal Medicine for Small Animals at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil.
Jaqueline Konrad: Department of Internal Medicine for Small Animals at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil.
Juliano Bortolini: Department of Statistics of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil.
Ana Carolina Schipiura: Department of Internal Medicine for Small Animals at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil.
Ana Flávia Borges de Freitas: Department of Internal Medicine for Small Animals at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil.
Sarah Szimanski Pazzini: Department of Clinical Pathology Laboratory at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil.
Arleana do Bom Parto Ferreira de Almeida: Department of Internal Medicine for Small Animals at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil.
Valéria Régia Franco Sousa: Department of Internal Medicine for Small Animals at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil.

doi: 10.14202/vetworld.2024.356-360

Article history: Received: 02-10-2023, Accepted: 18-01-2024, Published online: 15-02-2024

Corresponding author: Yolanda Paim Arruda Trevisan

E-mail: yolandapaim@hotmail.com

Citation: Trevisan YPA, de Freitas MS, de Freitas MN, Konrad J, Bortolini J, Schipiura AC, de Freitas AFB, Pazzini SS, de Almeida ADBPF, and Sousa VRF (2024) Influence of idiopathic epilepsy on blood pressure and electrocardiography in dogs treated with phenobarbital, Veterinary World, 17(2): 356-360.
Abstract

Background and Aim: Dogs with idiopathic epilepsy (IE) experience a shortened lifespan, neurobehavioral changes, and an increased risk of comorbidities during the interictal period. There have been several reports of sudden death in humans with epilepsy, suggesting changes in cardiac rhythm secondary to seizures. In veterinary medicine, there are still no such conclusive studies. The present study aimed to evaluate blood pressure values, electrocardiographic findings, and laboratory parameters in dogs with IE treated with phenobarbital and to correlate these findings with possible cardiac alterations.

Materials and Methods: Twenty-one dogs were divided into 11 healthy dogs and 10 idiopathic epileptic dogs for blood analysis, computerized electrocardiogram, and oscillometer-based blood pressure measurement.

Results: QRS complex and S-T interval values differed significantly between groups, but blood pressure values were not significantly different.

Conclusion: IE can occur with alterations in cardiac conduction and is a pathological condition.

Keywords: arterial hypertension, cardiac conduction, electrocardiogram, epileptic seizures, hemogasometry, tachycardia.