Antimicrobial resistance profiles of Escherichia coli derived from an integrated agroforestry-livestock system in Deli Serdang Regency, Indonesia

Vet World Vol.17 March-2024 Article-21

Research Article

Veterinary World, 17(3): 690-699

https://doi.org/10.14202/vetworld.2024.690-699

Rita Rosmala Dewi¹, Arif Nuryawan², Saleh Mohammed Jajere³, Juli Mutiara Sihombing¹, and Ika Julianti Tambunan⁴

1. Department of Animal Husbandry, Faculty of Science and Technology, Universitas Tjut Nyak Dhien, Medan, Indonesia.
2. Department of Forestry, Faculty of Forestry, Universitas Sumatera Utara, Medan, Indonesia.
3. Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, University of Maiduguri, Maiduguri, Borno State, Nigeria.
4. Department of Pharmacy, Faculty of Pharmacy, Universitas Tjut Nyak Dhien, Medan, Indonesia.

Background and Aim: Antimicrobial resistance (AMR) has become a significant global concern. Epidemiological data do not provide a robust description of the potential risks associated with AMR in the integrated agroforestry-livestock systems in Indonesia. Thus, the present study investigated the phenotypic and multidrug resistance (MDR) profiles of Escherichia coli strains isolated from the feces of livestock raised in the agro-silvopastoral system in Deli Serdang Regency, North Sumatra Province.

Materials and Methods: A standard microbiological culture procedure was followed to isolate the organism and test antibiotic susceptibility using the Kirby-Bauer disk diffusion protocol. Furthermore, the multiple antibiotic resistance index was determined. Univariate analysis was conducted to identify the risk factors associated with AMR.

Results: The vast majority (77.5%) of livestock farmers were aged >30 years. All farmers were men and had no higher education (100% of them). The majority of the animal species managed were cattle and goats (37.5% each) and the livestock grazing pasture system (67.5%). In addition, the majority of farmers reported high antimicrobial use on their farms (87.5%). Of the samples (n = 142) analyzed, n = 70 were positive, with an overall prevalence of 44.4%. The species-specific prevalences of E. coli were 32.5%, 47.8%, and 50% in buffalo, goat, and cattle, respectively. Ampicillin and tetracyclines exhibited high resistance levels among the studied animal species. A relatively lower MDR for E. coli was associated with grazing on the pasture.

Conclusion: The findings from the current study provide baseline epidemiological information for future robust studies aimed at elucidating the drivers and patterns of AMR in agro-silvopastoral systems in the study area or elsewhere.

Keywords: agro-silvopastoral, antimicrobial Resistance, Escherichia coli,Indonesia, livestock, multidrug resistance.

How to cite this article: Dewi RR, Nuryawan A, Jajere SM, Sihombing JM, and Tambunan IJ (2024) Antimicrobial resistance profiles of Escherichia coli derived from an integrated agroforestry-livestock system in Deli Serdang Regency, Indonesia, Veterinary World, 17(3): 690-699.

Received: 01-01-1970 Accepted: 01-01-1970 Published online: 22-03-2024

Corresponding author: Rita Rosmala Dewi E-mail: ritardewi@yahoo.com

DOI: 10.14202/vetworld.2024.690-699

Copyright: Dewi, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.