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              Open Access  
Copyright: The authors. This article is an open access 
article licensed under the terms of the Creative Commons Attribution License 
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distribution and reproduction in any medium, provided the work is properly 
cited. 
 
              
              
              Research 
              
              1.    Dhakeri-Bange 
              syndrome in goats due to Penicillium and Aspergillus spp, in Banke 
              district of Nepal: a clinical-laboratory investigation - 
              Kedar Karki, Purnima Manandhar and Om Prakash Neupane Vet World. 2008; 1(12): 357-359
   
              
              
          
 
              Abstract 
 
              An outbreak of 
              syndrome of unknown etiology associated with the feeding of moldy 
              dry forage and green fodder to goats in Dhakeri village of Banke 
              District. Goats suddenly became ill with symptoms of knuckling of 
              the fetlocks of the pelvic limbs, with no apparent ataxia or 
              flexor weakness. Weight bearing was possible while the digits were 
              extended, but with knuckling, weight was supported on the dorsal 
              surface of the foot .The more severely affected goats were 
              paraplegic and recumbent. Anorexia, apathy, diarrhea and ruminal 
              stasis, flaccid posterior paralysis,hindlegs stretched forward 
              both side of abdomin,paralysis of all four legs, head bented to 
              sides, aimlessly head and rear shaking .On clinical examination 
              based on history these goats were provisionally diagnosed as 
              Dhakeri-Bange as being called locally and Endemic Mycotic 
              polyneuropathy syndrome as seen first time in Nepal due to moldy 
              forage/fodder poisoning in natural pasture were treated with 
              Antidegnala liquor(sr). On mycological and microbiological 
              examination of tissue samples from post-mortem of dead goat and 
              forage/fodder samples from pasture and goats feeding stalls on 
              respective medium revealed the growth of fungal pathogens like 
              Aspergillus and Penicillium spp with E.coli.These results provide 
              circumstantial evidence that feeding of moldy forages and green 
              fodder leaves infected by Penicillium and Aspergillus spp may 
              cause outbreaks of a systemic Mycosis in these goats. 
              
              Keywords: Moldy 
              forage, greenfodder, Penicillium, Aspergillus Spp, Fungus, Goat, 
              Dhakeri-Bange, mycoticpolyneuropathy, Antidegnala liquor(s.r) . 
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