Open Access
Research (Published online: 08-10-2018)
5. Demographic aspects of human hydatidosis in Iranian general population based on serology: A systematic review and meta-analysis
Shirzad Gholami, Asal Tanzifi, Mehdi Sharif, Ahmad Daryani, Mohammad-Taghi Rahimi, Siavash Mirshafiee and Shahabeddin Sarvi
Veterinary World, 11(10): 1385-1396

Shirzad Gholami: Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Asal Tanzifi: Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Iran; Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
Mehdi Sharif: Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Ahmad Daryani: Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Mohammad-Taghi Rahimi: School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.
Siavash Mirshafiee: Department of Husbandry, Ghaemshahr Branch of Islamic Azad University, Iran.
Shahabeddin Sarvi: Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Iran.

doi: 10.14202/vetworld.2018.1385-1396

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Article history: Received: 23-04-2018, Accepted: 28-08-2018, Published online: 08-10-2018

Corresponding author: Shahabeddin Sarvi


Citation: Gholami S, Tanzifi A, Sharif M, Daryani A, Rahimi M, Mirshafiee S, Sarvi S (2018) Demographic aspects of human hydatidosis in Iranian general population based on serology: A systematic review and meta-analysis, Veterinary World, 11(10): 1385-1396.

Aim: Human cystic echinococcosis (CE), caused by the larval stage of Echinococcus granulosus cestodes, is a globally distributed chronic disease that is an important socioeconomic and public health problem in humans and livestock in developing countries, including Iran. The aim of this study was to determine the overall seroprevalence of hydatid infection in the general population of Iran.

Materials and Methods: This systematic review began by searching electronic databases in English (PubMed, Science Direct, Scopus, and Google Scholar) and Persian (Magiran, Scientific Information Database, Iran Medex, and Iran Doc).

Results: Our search resulted in a total of 40 reports published from 1995 to 2015. Of 49,460 individuals surveyed, 3090 cases of hydatidosis were reported. Community-based studies showed that the seroprevalence of CE in the Iranian general population was 6.0% (95% confidence interval: 5.0-7.0%). The age group with the highest CE seroprevalence was 20-40 years, and the lowest one was in the under 20 year's group. The seroprevalence of hydatidosis in males was significantly higher than that in females. In addition, the intended rate was significantly higher in rural regions than in urban areas.

Conclusion: Management program for developing more efficient diagnostic tests should be established. Further, cost-effective preventive approaches, including relevant research, should be considered. Finally, hydatid cyst control programs that are important for interrupting the transmission of human CE should be improved.

Keywords: cystic echinococcosis, diagnosis, general population, hydatidosis, Iran, seroprevalence.


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