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Research
3.
Study of antiulcer activity of Bauhinia racemosa lam in
rats -
V. I. Borikar, C.R. Jangde, Preety Philip, D.S. Rekhe and S. K.
Atole
Vet World. 2009; 2(6): 217-218
Abstract
An
experiment was conducted to study the antiulcer effect of the
dried fruit powder of the plant Bauhinia racemosa in
Wistar albino rats. Thirty Wistar rats of either sex weighing
between 150 - 200gm were selected and divided into five groups,
each comprising of six rats.
The rats were divided into 5 groups T1
T2,
T3,
T4,
and T5
and were
given 0.5 ml normal saline, aqueous extract in the dose rate
of100mg/kg body weight, 200mg/kg body weight, alcoholic extract
@100mg/kg body weight and 200mg/kg body weight respectively.
After one hour all the groups were administered Paracetamol at a
dose rate of 200mg/kg body weight orally. After 24hrs, the
number of ulcers, ulcer score, percent incidence, ulcer index
and healing index were recorded. From the results obtained it
was concluded that aqueous extract in the dose rate of 200mg/kg
body weight and alcoholic extract (100mg/kg & 200mg/kg body
weight) could produce antiulcer activity.
Keywords:
Bauhinia racemosa,
Paracetamol, antiulcer activity
