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Research
5.
Acute toxicity study of Vilocym premix (herbal growth promoter
for Livestock)in wistar albino rat -
A. H. Ahmad, D. S. Rekhe, K. Ravikanth, S. Maini
Vet World. 2009; 2(3): 100-102
Abstract
An
experimental study with the objective of safety evaluation of
Vilocym Premix, herbal growth promoter for Livestock (supplied
by Ayurvet Ltd., Baddi, India), was done as per standard
guidelines of OECD-423 for acute toxicity testing. Vilocym
Premix is a scientifically developed combination of herbs that
contains herbal ingredients namely Azadirachta indica,
Curcuma longa & many more alongwith natural zeolites. The
study was done in 3 males and 3 female Wistar Albino rats, which
were administered an initial dose of 50 mg/kg body weight
followed by dose rates of 300, 500 & 5000 mg/kg body weight of
test compound. The animals were observed for signs of
convulsions, tremors, circling, depression, excitement and
mortality. Body weight was recorded at 0,7th
and 14th
day and plasma total protein; albumin; AST and ALT were measured
after 3rd
day of experiment. No abnormal sign of symptoms were observed in
any of the animal fed with Vilocym Premix at the dose rate of
50, 300, 500 & 5000 mg/kg. No mortality was observed indicating
safety of herbal premix.
Keywords:
Growth Promoter, Herbal, Livestock, Toxicity, Production, Weight
gain.
