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Copyright: The authors. This article is an open access article licensed under the terms of the Creative Commons Attribution License ( which permits unrestricted use, distribution and reproduction in any medium, provided the work is properly cited.

Original Research

3. Treatment protocol with progesterone, estradiol and oxytocin to improve conception rate and allows for early diagnosis of pregnancy in black bengal goat - D Sengupta, S Basu
Vet World. 2012; 5(5): 269-273


This work was performed to develop a treatment protocol that will shorten the length of estrous cycle in mated goats those fail to conceive, without reduction in conception rate. In experiment 1, ninety goats (single parity, 1 to 2 years age) were divided into nine groups of ten goats each. On return to heat, all groups were mated barring groups 1, 3 and 4. On days 3-5 of estrous, progesterone was treated at the dose rate of 10 mg i.m (groups 3, 5 and 7) or 30 mg i.m. (groups 4, 6 and 8). Groups 7, 8 and 9 received estradiol (500 g i.m.; day 8) + oxytocin (10 IU i.m.; day 9) treatment. Following treatments, the goats were observed for heat and appearance of embryonic vescicles (EV) by transabdominal ultrasonography. In experiment 2, group 2 (n=50) was equal to group 8 of experiment 1 and group 1 (n=50) served as control. The litter size and weight was recorded at birth. Early progesterone treatment significantly (P<0.05) shortened the cycle length in groups 3 (day 15) and 4 (day 17) respectively compared to control (group 1; 21 days), whereas mated group 5 and 6 did not have any difference in conception rate compared to control (group 2). In does of group 5 & 6, EVs were observed much earlier than group 2. Estradiol + oxytocin treatment had no effect on conception rate of group 8, while does of group 7 and 9 returned to heat on day 12. In experiment 2, significant difference in conception rate and percentage of single, double, triplet and quadruplet born was observed between control and treated groups while the mean litter weight born was non-significant. Thus early pregnancy diagnosis can be done at by progesterone + estrogen treatment that not only shortens the length of estrous cycle, if the animals fail to conceive, but also improves the conception rate.

Key words: progesterone, estrogen, oxytocin, estrous cycle length, pregnancy, Black Bengal goats