Veterinary World


ISSN (Online): 2231-0916


 Editorial board

 Instructions for authors

 Reviewer guideline

 Open access policy





Open Access

Copyright: The authors. This article is an open access article licensed under the terms of the Creative Commons Attribution License ( which permits unrestricted use, distribution and reproduction in any medium, provided the work is properly cited.

Original Research (Published online : 07-02-2013)
8. Blood antioxidant profile and lipid peroxides in dairy cows with clinical mastitis
- Ricky Jhambh, Umesh Dimri, Vinod Kumar Gupta and Rajesh Rathore
Vet World. 2013; 6(5): 271-273

Aim: To evaluate blood antioxidant profile and lipid peroxides in dairy cows with clinical mastitis.

Materials and Methods: Twelve cases of clinical mastitis in cross-bred cows were selected based on physical examination of udder and milk, California Mastitis Test (CMT), Somatic Cell Count (SCC) and confirmation by bacteriological examination of milk and requisite biochemical tests. Twelve lactating cows showing negative CMT reaction and SCC <2x105 cells/ml were considered as healthy control. Antioxidant parameters measured in blood were superoxide dismutase (SOD), catalase activities and reduced glutathione (GSH) concentration. Erythrocytic lipid peroxidation (LPO) was measured in terms of malondialdehyde (MDA) production.

Results: Significant (P<0.05) decrease in blood SOD and catalase activities, GSH concentration and an increase in erythrocytic lipid peroxides was observed in cows with clinical mastitis.

Conclusion: It is concluded that there is a compromise in antioxidant defense of the body in dairy cows with clinical mastitis resulting in oxidative damage, therefore, necessitate the use of antioxidants and other protective compounds along with conventional therapy for mastitis control.

Keywords: catalase, clinical mastitis, dairy cows, glutathione, lipid peroxides, superoxide dismutase