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Research (Published online: 23-12-2014)

14. Comparative efficacy of crystalloid and colloid-crystalloid combination for the management of hemorrhagic gastroenteritis in dogs - Chandreyee Sen, Ashwani K. Sharma and P. S. Dhaliwal

Veterinary World, 7(12): 1108-1112



   doi: 10.14202/vetworld.2014.1108-1112



Chandreyee Sen: Department of Veterinary Medicine, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India;

Ashwani K. Sharma: Department of Veterinary Medicine, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India;

P. S. Dhaliwal: Department of Veterinary Medicine, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India;


Received: 21-06-2014, Revised: 10-10-2014, Accepted: 16-10-2014, Published Online: 23-12-2014


Corresponding author: Chandreyee Sen, e-mail:

Aim: In the present study, a therapeutic trial was conducted to assess comparative efficacy of crystalloid plus colloid and crystalloid intravenous infusions alone as fluid therapy in dogs suffering from hemorrhagic gastroenteritis (HGE).

Materials and Methods: 20 dogs manifesting HGE, presented at Teaching Veterinary Clinical Services Complex, Ludhiana, Punjab, were selected randomly for the trial. All of them were observed to suffer from moderate dehydration on clinical examination. Crystalloids 5% DNS and RL were used in combination with polygelin 3.5% colloidal solution in the first group (Combination I) and in the second group, the afore-said crystalloids (Combination II) were used, both groups consisting of 10 cases each. Antibiotics and symptomatic treatment were same for all the 20 cases. The outcome of both treatment groups was evaluated on hemato-biochemical parameters, before and after administration of the therapies and compared statistically within and between the two groups. Hemato-biochemical parameters of eight clinically healthy animals were considered as control for comparison.

Result: On hemato-biochemical examination, significant alterations were observed in leucogram, platelet and serum globulin concentration after the treatment in the first group as compared to before treatment values. In the second group, mean hemoglobin varied significantly after the treatment. After therapies were administered, significant difference in serum globulin level and albumin: Globulin was found in between the treatment groups (Combination I and Combination II). Clinical recovery was faster in the first group than the second group of animals.

Conclusion: On hemodynamic and laboratory data, efficacies of both the fluid therapies were equivocal. Colloidal solutions may hasten recovery in small animals suffering from gastrointestinal crisis.

Keywords: colloid, crystalloid, dog, hemato-biochemical studies, hemorrhagic-gastroenteritis.

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