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              Open Access  
Copyright: The authors. This article is an open access 
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              Research 
(Published 
online: 29-12-2014) 
              23. 
              Therapeutic efficacy of different Hemodialysis prescriptions in 
              canine azotemia - 
              Ekta Atul Thakkar and Rajiv V. Gaikwad 
              
              Veterinary World, 7(12): 1150-1156 
                
              
   
                
                
doi: 
              10.14202/vetworld.2014.1150-1156 
                  Ekta 
              Atul Thakkar: 
              
              Department of Veterinary Clinical Medicine, Ethics and 
              Jurisprudence, Bombay Veterinary College, Parel, Mumbai, 
              Maharashtra, India;
              
              ektaathakkar@gmail.com 
              Rajiv V. Gaikwad: Department of Veterinary Clinical Medicine, 
              Ethics and Jurisprudence, Bombay Veterinary College, Parel, 
              Mumbai, Maharashtra, India; Department of Veterinary Clinical 
              Medicine, Ethics and Jurisprudence and I/C Department of 
              Veterinary Nuclear Medicine, Bombay Veterinary College, Parel, 
              Mumbai, Maharashtra, India;
              
              drrvg2001@gmail.com   
              Received: 29-07-2014, Revised: 05-11-2014, Accepted: 20-11-2014, 
              Published online: 29-12-2014   
              
              
              Corresponding author:
              
              Rajiv V. Gaikwad, email: drrvg2001@gmail.com 
 
              Abstract 
 Aim:
              The aim was to determine therapeutic efficacy of different 
              Hemodialysis prescriptions in canine azotemia. 
              Materials and Methods: Patients (n=9) with acute onset of 
              renal dysfunction or chronic patients with superimposed acute 
              factor (component) or patients with known chronic nature of the 
              disease were dialyzed with Fresenius 4008S hemodialysis machine 
              after jugular catheterization. Patients were randomly divided into 
              two groups, one group (n=3) was dialyzed every day and second 
              (n=4) was dialyzed on alternate days. The patients were evaluated 
              for following parameters to compare the efficacy of the dialysis 
              prescription: Urea reduction ratio (URR), creatinine reduction 
              ratio (CRR), Kt/V, time averaged concentration of urea (TAC urea). Result 
              and Discussion: Increasing both dialysis frequency and 
              duration is the superior dialysis schedule. Patient dialyzed every 
              day with total processed blood volume 1.79 L/Kg for 4 h 26 
              min/session had the lowest TAC of 36.82 mg/dl, thereby was 
              considered it as a better prescription. 
              Keywords: creatinine reduction ratio, 
              hemodialysis, Kt/V, time averaged concentration of urea, urea 
              reduction ratio. 
 
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