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Research
(Published
online: 15-09-2014)
12.
Thoracic radiography and oxidative
stress indices in heartworm affected dogs - P. K. Rath,
S. K. Panda, B. P. Mishra, R. C. Patra and
I. Nath
Veterinary World, 7(9): 689-692
doi:
10.14202/vetworld.2014.689-692
P.
K. Rath:
Department of Veterinary Pathology, College of Veterinary Science
& Animal Husbandry, OUAT, Bhubaneswar, Odisha, India;
drpkrath78@gmail.com
S.
K. Panda:
Department of Veterinary Pathology, College of Veterinary Science
& Animal Husbandry, OUAT, Bhubaneswar, Odisha, India;
drsusen_panda@yahoo.com
B.
P. Mishra:
Veterinary Dispensary, Rajsunakhala, Nayagarh, Odisha, India;
bidyutmishraivri@gmail.com
R.
C. Patra:
Department of Clinical Veterinary Medicine, College of Veterinary
Science & Animal Husbandry, OUAT, Bhubaneswar, Odisha, India;
rcpatra@gmail.com
I.
Nath: Department of Veterinary Surgery & Radiology, College of
Veterinary Science & Animal Husbandry, OUAT, Bhubaneswar, Odisha,
India; indravet@yahoo.co.in
Received: 30-05-2014, Revised: 25-07-2014, Accepted: 31-07-2014,
Published online: 15-09-2014
Corresponding author:
P. K. Rath, e-mail: drpkrath78@gmail.com
Abstract
Aim:
The aim was to study the pathomorphological changes through
thoracic radiography and status of oxidative stress parameters in
heartworm affected dogs in Odisha.
Materials and Methods: A total of 16 dogs with clinically
established diagnosis of dirofilariasis by wet blood smear and
modified Knott’s test and equal numbers of dogs as control were
included in this study. The present study was conducted in
heartworm affected dogs to see the pathomorphological changes
through thoracic radiography. Similarly, the evaluation was
undertaken for observing any alterations in oxidative stress
status in affected as well as non-affected, but healthy control
dogs by adopting standard procedure.
Results: Thoracic radiography revealed cardiac enlargement,
round heart appearance suggestive of right ventricular
hypertrophy, tortuous pulmonary artery and darkening of lungs.
Alterations in oxidative stress indices showed a significant rise
of lipid peroxidase activity, non-significant rise of superoxide
dismutase and a significant although reverse trend for catalase
levels in affected dogs in comparison to Dirofilaria
negative control but apparently healthy dogs.
Conclusions: Radiographic changes, as well as alterations in
oxidative stress parameters, may not be diagnostic for heartworm
infection, but useful for detecting heartworm disease, assessing
severity and evaluating cardiopulmonary parenchyma changes and
gives a fair idea about the degree of severity of the disease. It
aids as contributing factors in disease pathogenesis.
Keywords: Dirofilaria immitis, heartworm, oxidative
stress, radiography.
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