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              Open Access  
Copyright: The authors. This article is an open access 
article licensed under the terms of the Creative Commons Attribution License 
 
 
(http://creativecommons.org/licenses/by/2.0) which permits unrestricted use, 
distribution and reproduction in any medium, provided the work is properly 
cited. 
 
              
              
              Research 
(Published 
online: 06-09-2014) 
              
              5. 
              Efficacy of fowl pox 
              vaccines against Egyptian isolated strain during 2012 - 
              Susan S El-Mahdy and Christine Mikheal 
              
              Veterinary World, 7(9): 656-660   
              
   
                
                
doi: 
              10.14202/vetworld.2014.656-660 
                
                Susan S 
              El-Mahdy: Central 
              Laboratory for Evaluation of Veterinary Biologics, El-Seka El-Beida 
              St. Abbasia 131, Cairo, Egypt; prof.s.elemahdy@gmail.com 
              Christine Mikheal: Department of Pox Vaccines Veterinary Serum 
              and Vaccine Research Institute, El Seka El-Beida St. Abbasia, 
              Cairo, Egypt; 
              chochichach@yahoo.com   Received: 
              01-05-2014, Revised: 16-07-2014, Accepted: 21-07-2014, Published 
              online: 06-09-2014   
              
              
              Corresponding author: Susan S. El-mahdy, 
              email: prof.s.elemahdy@gmail.com 
 
              Abstract 
 Aim:
              This study was designed to evaluate the protection induced by 
              different commercial fowl pox (FP) vaccines against local FP virus 
              isolated from Giza governorate in Egypt during 2012. 
              Materials and Methods: Efficacy of FP vaccines against local 
              field isolates was determined in seven groups of (20 birds/group) 
              6 weeks old specific-pathogen free chicks. Each group was 
              vaccinated via wing web with one of different FP living vaccines 
              and (20) chicks in group (8) did not receive any FP vaccine and 
              served as controls. At the 3rd, 5th, 
              7th and 10th-da 
              post-vaccination (DPV), all birds were examined for the presence 
              of takes at the site of vaccination. Three weeks post vaccination, 
              serum samples were collected, and the levels of induced antibodies 
              were detected by passive hemagglutination (PH) test. All birds in 
              Groups (1-8A) were challenged individually via the wing web with 
              EID50 103.0 of the 
              Egyptian isolated strain during 2012. 
              Results: Takes detected at the site of vaccination at the 3rd
              day were ranging from 45 to 70%. This percent 
              increased to 80-95% at the 5th DPV with a 
              maximum elevation of takes at the 7th DPV 
              (90-100%). Geometric mean titer of PH assay antibody titer, 3 
              weeks post vaccination, was ranging between 5.60 and 9.60 
              according to the type of vaccine used and with protection 90-100%. 
              Conclusion: Efficacy of some commercial FP vaccines used in 
              the poultry field against the Egyptian isolated strain during 2012 
              ranged between 90% and 100% according to the type of used vaccine.
               
              Keywords: chickens, fowl pox vaccines, local 
              Egyptian isolated strain. 
 
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