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Research (Published online: 14-07-2015)

8.  Seroprevalence of foot and mouth disease virus infection in pigs from Zuru, Nigeria - L. U. Fakai, O. O. Faleke, A. A. Magaji, E. B. Ibitoye and B. R. Alkali

Veterinary World, 8(7): 865-869



   doi: 10.14202/vetworld.2015.865-869


L. U. Fakai: Zonal Veterinary Clinic, Kebbi, Nigeria;

O. O. Faleke: Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, Usmanu Danfodiyo University, Sokoto, Nigeria;

A. A. Magaji: Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, Usmanu Danfodiyo University, Sokoto, Nigeria;

E. B. Ibitoye: Department of Theriogenology and Animal Production, Faculty of Veterinary Medicine, Usmanu Danfodiyo University, Sokoto, Nigeria;

B. R. Alkali: Department of Veterinary Microbiology, Faculty of Veterinary Medicine, Usmanu Danfodiyo University, Sokoto, Nigeria;


Received: 05-02-2015, Revised: 10-06-2015, Accepted: 19-06-2015, Published online: 14-07-2015


Corresponding author: E. B. Ibitoye, e-mail:

Citation: Fakai LU, Faleke OO, Magaji AA, Ibitoye EB, Alkali BR (2015) Seroprevalence of foot and mouth disease virus infection in pigs from Zuru, Nigeria, Veterinary World 8(7): 865-869.

Aim: This study was conducted to determine the seroprevalence and distribution of foot and mouth disease virus (FMDV) infection in pigs from Zuru, Kebbi State, Nigeria.

Materials and Methods: Cross-sectional serological surveys were conducted between May and December 2013 using the immunochromatography assay technique. Structured questionnaires were administered to households identified at pig rearing areas to obtain the population structures and some information on managemental practices.

Results: A total number of 849 pigs were enumerated at 37 pigs rearing households. Tudun wada had the largest concentration of pigs (237 pigs), while Dabai has the least (38 pigs). A total of 250 blood samples were collected, of which 45 (18%) were positive; Zango has the highest seroprevalence (1.6%), while Dabai recorded the least (0.4%). Based on sex and age, the infection was higher in female (10.4%) and young pigs (11.6%) than male (7.6%) and adult pigs (6.4%), respectively. There was no significant (p>0.05) association between infection and pig rearing areas, sex, and age. Furthermore, none of the 250 pigs examined for classical FMDV lesions was positive.

Conclusion: The results of this study showed that FMD is an important disease of pigs in the study areas. This result justifies the need for more attention and subsequent molecular study to identify the circulating FMDV in the area, which will help in the implementation of effective control measures.

Keywords: foot-and-mouth disease virus, immunochromatography, Nigeria, pigs, seroprevalence.

1. OIE. (2008) Foot and mouth disease. In: Manual of Diagnostic Tests and Vaccines for Terrestrial Animals. 6th ed., Ch. 2.1.5. World Organisation for Animal Health (OIE), Paris, France.
2. Mohamoud, A., Tessema, E. and Degefu, H. (2011) Seroprevalence of bovine foot and mouth disease (FMD) in Awbere and Babille districts of Jijiga zone, Somalia Regional State, Eastern ethiopia. Afr. J. Microbiol. Res., 5(21): 3559-3563.
3. Office International des Epizooties (OIE). (2012) Foot and Mouth Disease. Ch. 2.1.5. OIE Terrestrial Mannual, Paris, France. p1-29.
4. Broonsvoort, B.M., Hamman, S.M., Tanya, V.N., Kitching, R.P. and Morgan, K.L. (2004) Risk factors for herdsman-reported foot and mouth disease in the Adamawa province of Cameroon. Prev. Vet. Med., 66(1-4): 127-139.
5. FAO/OIE. (2012) Global Conference on Foot and Mouth Disease Control: Wildlife and Foot and Mouth Disease, A look from the Wild Side. Bangkok, Thailand 27-29 June. p1-44.
6. Lubroth, J., Rodri'guez, L. and Dekker, A. (2006) Vesicular diseases. In: Straw, B.E., Zimmerman, J.J., D'Allaire, S. and Taylor, D.J., editors. Diseases of Swine. 9th ed. Blackwell Publishing Professional, Ames, Iowa, USA. p517-536.
7. Alexandersen, S., Zhang, Z., Donaldson, A.L. and Garland, A.J.M. (2003) The pathogenesis and diagnosis of foot and mouth disease. J. Compr. Pathol., 129: 268-282.
8. EMPRESS. (2007) FOCUS ON: Foot and mouth disease, situation worldwide and major epidemiological events in 2005-2006. EMPRESS Focus Bull, 1: 1-11.
9. Yamazaki, W., Mioulet, V., Murray, L., Madi, M., Haga, T., Misawa, N., Horii, Y. and King, D.P. (2013) Development and evaluation of multiplex RT-LAMP assays for rapid and sensitive detection of foot-and-mouth disease virus. J Virol. Methods, 192: 18-24.
10. Kibore, B., Gitao, C.G., Sangula, A. and Kitala, P. (2014) The epizootiology of foot-and-mouth disease in high risk zones in Kenya. Am. J. Res. Commun., 2(9): 129-154.
11. Leon, E.A. (2012) Foot and mouth disease in pigs: Current epidemiological situation and control methods. Transbound. Emerg. Dis., 59: 36-49.
12. Alexandersen, S. and Donaldson, A.I. (2002) Further studies to quantify the dose of natural aerosols of foot-and-mouth disease virus for pigs. Epidemiol. Infect., 128: 313-323.
PMid:12002550 PMCid:PMC2869825
13. Gloster, J., Doel, C., Gubbins, S. and Paton, D.J. (2008) Foot-and-mouth disease: measurements of aerosol emission from pigs as a function of virus strain and initial dose. Vet. J., 177: 374-380.
14. Lazarus, D.D., Schielen, W.J.G., Wungak, Y., Kwange, D. and Fasina, F.O. (2012), Sero-epidemiology of foot-and-mouth disease in some Border States of Nigeria. Afr. J. Microbiol. Res., 6(8): 1756-1761.
15. Lazarus, D.D., Adamu, S.S., Shamaki, D. and Fasina, F.O. (2010) Foot-and-mouth disease virus situation in Nigeria. Book of Abstract EuFMD Week 2010. European Commission for the Control of Foot-and-Mouth Disease, Research Group of the Standing Technical Committee, Vienna-Austria, 28th September – 1st October 2010. p139-140.
16. Kitching, R.P. and Alexandersen, S. (2002), Clinical variation in foot and mouth disease: Pigs. Rev. Sci. Tech. Off. Int. Epizoot., 21: 513-518.
17. Williams, S. (2003) Persistence of Disease Agents in Carcasses and Animal Products. Animal Health Australia, Australia. p1-171.
18. Kitching, R.P. and Hughes, G.J. (2002) Clinical variation in foot and mouth disease: Sheep and Goats. Rev. Sci. Tech. Off. Int. Epizoot., 21: 505-512.
19. Yatswako, S., Faleke, O.O., Gulumbe, M.L. and Daneji, A.I. (2007) Cryptosporidium oocysts and Balantidium cyst in pigs reared semi-intensively in Zuru, Nigeria. Pak. J. Biol. Sci., 10: 3435-3439.
20. National Bureau of Statistics (NBS). (2007) General Household Survey Report, 1995 – 2005. Federal Republic of Nigeria. March 2007.
21. Thrusfield, M. (1997), Estimation of disease prevalence. In: Veterinary Epidemiology. 2nd ed. Blackwell Science. p182-187.
22. Hassan AZ, Hassan FB. Basic Clinic Services. In: An Introduction to Veterinary Practice. 1st ed. 2003. p. 57.
23. Bronsvoort, B.M. de C., Radford, A.D., Tanya, V.N., Nfon, C., Kitching, R.P. and Morgan K.L. (2004) Molecular epidemiology of foot and mouth disease virus in the Adamawa province of Cameroon. J. Clin. Microbiol., 42(5): 2186-2196.
24. Dukpa, K., Robertson, I.D. and Ellis, T.M. (2011) The seroprevalence of foot-and-mouth disease in the sedentary livestock herds in four districts of Bhutani. Prev. Vet. Med., 100: 231-236.
25. OIE-PVS. (2010) Tool for the evaluation of performance of veterinary services. 5th ed. Available from: http:// to-oie-members/pvs-evaluations/oie-pvs-tool/. [Last accessed on 2011 Apr 25].
26. Sule, A. (1998) Farmer-pastoralist conflict: The gombe state experience. Proceedings of the Workshop on National Fadama Development Project Held at the State House of Assembly Building, Bauchi. p12-32.
27. Kachia Grazing Reserve. (2011) March 2011 Review of Fieldwork. ICONZ Nigeria Case Study Documents. 28 Esayas, G., Gelagay, A., Tsegalem, A. and Kassahun, A. (2009). Seroprevalence of foot and mouth disease in Bench Maji zone, southwestern Ethiopia. J. Vet. Med. Anim. Health, 1: 5-10.
29. Megersa, B., Beyene, B., Abunna, F., Regassa, A., Amenu, K. and Rufael, T. (2009) Risk factors for foot and mouth disease seroprevalence in indigenous cattle in Southern Ethiopia: The effect of production system. Trop. Anim. Health Prod., 41: 891-898.
30. Rovid Spickler, A., Roth, J.A., Gaylon, J. and Lofstedt, J. (2010) Emerging and Exotic Diseases of Animals. 4th ed. Iowa State University, Iowa.