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cited.
R esearch
(Published online:
10-06-2015)
4.
Hematobiochemical changes in ehrlichiosis in
dogs of Anand region, Gujarat - C. M. Bhadesiya and S.
K. Raval
Veterinary World, 8(6): 713-717
doi:
10.14202/vetworld.2015.713-717
C.
M. Bhadesiya:
Department of Veterinary Medicine, College of Veterinary Science
and Animal Husbandry, Anand Agricultural University, Anand,
Gujarat, India;
dr.chirag64164@gmail.com
S.
K. Raval: Department of Veterinary Medicine, College of
Veterinary Science and Animal Husbandry, Anand Agricultural
University, Anand, Gujarat, India;
skraval23@rediffmail.com
Received: 22-03-2015, Revised: 05-05-2015, Accepted: 11-05-2015,
Published online: 10-06-2015
Corresponding author:
C. M. Bhadesiya, e-mail: dr.chirag64164@gmail.com
Citation:
Bhadesiya CM, Raval SK
(2015) Hematobiochemical changes in ehrlichiosis in dogs of Anand
region, Gujarat, Veterinary World 8(6): 713-717.
Abstract
Aim:
The present research work was undertaken to study the
diagnostic importance of hematobiochemical changes in naturally
occurring ehrlichiosis in dogs of Anand region, Gujarat
irrespective of their age, breed, and sex.
Materials and Methods: Blood samples from a total of 29 dogs
of Anand region of Gujarat state were screened for detection of
anti-Ehrlichia canis antibodies using Immunocomb ®
rapid diagnostic kit (Biogal Galed Laboratories,
Israel) and subjected to estimation of hematobiochemical
parameters by auto hematology analyzers at College of Veterinary
Science and Animal Husbandry, Anand. Statistical analysis,
interpretation and comparison of hematobiochemical changes with
scientific literature was carried out in order to understand the
pathophysiology of the disease.
Results: Of 29 dogs, 18 were positive for
naturally occurring ehrlichiosis based on the presence of anti-E.
canis antibodies while 11 were negative. Haematology evinced
that the mean values of hemoglobin, total erythrocyte counts,
platelet count and packed cell volume in dogs with ehrlichiosis
decreased significantly (p<0.01) in comparison to healthy dogs.
Among differential leucocyte count, mean values of lymphocytes
decreased, neutrophils increased, eosinophils decreased and
basophils decreased significantly (p<0.05) in dogs with
ehrlichiosis in comparison to healthy dogs while statistically
nonsignificant (p>0.05) difference was observed in values of
monocytes in dogs with ehrlichiosis and healthy dogs. Among
various red blood cells indices, the mean values of mean
corpuscular hemoglobin concentration increased significantly
(p<0.01) in dogs with ehrlichiosis in comparison to healthy dogs.
Serum biochemistry revealed significant (p<0.01) increase in serum
glutamic pyruvic transaminase, serum glutamic oxaloacetic
transaminase and creatinine levels as well as decrease in total
protein levels in dogs with ehrlichiosis as compared to healthy
dogs.
Conclusion: Clinical importance of hematobiochemical changes
in 18 natural cases of ehrlichiosis in dogs of Anand region,
Gujarat irrespective of their age, breed and sex is discussed,
which would aid new insights in diagnosis and therapeutic
management.
Keywords: dogs, ehrlichiosis, anti-Ehrlichia
canis antibodies, hematobiochemical changes.
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