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R esearch
(Published online: 04-03-2015)
2.
Evaluation of efficacy and safety of glycopyrrolate - xylazine -
propofol anesthesia in buffalo calves -
Sandeep Potliya, Ashok
Kumar, Sandeep Kumar, Sukhbir Singh and Sarvan Kumar
Veterinary World, 8(3): 251-256
doi:
10.14202/vetworld.2015.251-256
Sandeep Potliya:
Department of Veterinary Surgery and Radiology, College of
Veterinary Science, Lala Lajpat Rai University of Veterinary and
Animal Sciences, Hisar, Haryana, India;
sandeeppotliya@gmail.com
Ashok Kumar:
Department of Veterinary Surgery and Radiology, College of
Veterinary Science, Lala Lajpat Rai University of Veterinary and
Animal Sciences, Hisar, Haryana, India;
professorashokkumar@gmail.com
Sandeep Kumar:
Department of
Veterinary Physiology and Biochemistry, College of Veterinary
Science, Lala Lajpat Rai University of Veterinary and Animal
Sciences, Hisar, Haryana, India;
drsandgupta@gmail.com
Sukhbir Singh:
Department of Veterinary Surgery and Radiology, College of
Veterinary Science, Lala Lajpat Rai University of Veterinary and
Animal Sciences, Hisar, Haryana, India;
profsukhbir@rediffmail.com
Sarvan Kumar: Department of Veterinary Pathology, College of
Veterinary Science, Lala Lajpat Rai University of Veterinary and
Animal Sciences, Hisar, Haryana, India;
drsrvn38@gmail.com
Received: 03-09-2014, Revised: 12-01-2015, Accepted: 20-01-2015,
Published online: 04-03-2015
Corresponding author:
Sandeep Potliya, e-mail: sandeeppotliya@gmail.com
Citation:
Potliya S,
Kumar A, Kumar S, Singh S, Kumar S (2015) Evaluation of efficacy
and safety of glycopyrrolate - xylazine - propofol anesthesia in
buffalo calves, Veterinary World 8(3):251-256.
Abstract
Aim:
To evaluate the efficacy and safety of glycopyrrolate -
xylazine - propofol anesthesia in buffalo calves.
Materials and Methods: The study was conducted on six
clinically healthy male buffalo calves, 6-12 months of age, and
weighing between 130 and 170 kg. In all the animals;
glycopyrrolate (0.01 mg/kg, IM), xylazine (0.1 mg/kg, IM) and 1%
propofol as single bolus (1.5 mg/kg, intravenous), were
administered. The parameters observed included behavioral changes,
physiological; hematological and blood biochemical parameters.
Results: Muzzle and nostrils became dry in all the animals
after glycopyrrolate administration. A decrease in spontaneous
activity and mild cutaneous analgesia was noticed after xylazine
administration. After administration of propofol, loss of
swallowing reflex, palpebral reflex, corneal reflexes, periosteal
reflex and complete analgesia was observed. There was no
significant change in rectal temperature and heart rate. However,
heart rate remained elevated during anesthesia. Respiratory rate
decreased significantly after propofol administration. There was a
significant increase in plasma glucose after the xylazine and
propofol administration which remained elevated till recovery. A
significant decrease in chloride level was seen after propofol
administration.
Conclusions: Glycopyrrolate - xylazine - propofol anesthetic
combination may safely be used for short duration anesthesia in
buffalo calves.
Keywords: buffalo calves, propofol, xylazine,
glycopyrrolate.
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