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Research (Published online: 21-11-2015)

6. Therapeutic management of botulism in dairy cattle - S. Jegaveera Pandian, M. Subramanian, G. Vijayakumar, G. A. Balasubramaniam and K. Sukumar

Veterinary World, 8(11): 1305-1309



   doi: 10.14202/vetworld.2015.1305-1309


S. Jegaveera Pandian: Division of Livestock and Fisheries Management, ICAR Research Complex for Eastern Region, Patna, Bihar, India;

M. Subramanian: Department of Veterinary Clinical Medicine, Veterinary College and Research Institute, Namakkal- 637 002, Tamil Nadu, India;

G. Vijayakumar: Department of Veterinary Clinical Medicine, Veterinary College and Research Institute, Namakkal- 637 002, Tamil Nadu, India;

G. A. Balasubramaniam: Department of Veterinary Pathology, Veterinary College and Research Institute, Namakkal- 637 002, Tamil Nadu, India;

K. Sukumar: Department of Veterinary Public Health and Epidemiology, Veterinary College and Research Institute, Tirunelveli- 627 001, Tamil Nadu, India;


Received: 08-06-2015, Revised: 26-10-2015, Accepted: 05-10-2015, Published online: 21-11-2015


Corresponding author: S. Jegaveera Pandian, e-mail:

Citation: Pandian SJ, Subramanian M, Vijayakumar G, Balasubramaniam GA, Sukumar K (2015) Therapeutic management of botulism in dairy cattle, Veterinary World 8(11): 1305-1309.

Aim: To report the successful recovery of few dairy cattle from botulism in response to a modified therapeutic strategy.

Materials and Methods: Seventy four naturally-occurring clinical cases of bovine botulism encountered during the period of 2012-2014 which were confirmed by mouse lethality test became material for this study. Affected animals were made into three groups based on the treatment modifications made during the course of study.

Results and Discussion: With the modified therapeutic regimen, 17 animals recovered after 7-10 days of treatment. Clinical recovery took 2-30 days. Animals which were not given intravenous fluid and calcium recovered uneventfully. Cattle which were already treated with intravenous fluids, calcium borogluconate, and antibiotics did not recover. They were either died or slaughtered for salvage.

Conclusion: In cattle with botulism, administration of Vitamin AD3E and activated charcoal aid the clinical recovery. Besides, strictly avoiding anti-clostridial antibiotics, fluid therapy, and calcium therapy may facilitate the clinical recovery. Upon fluid administration, the pulmonary congestion existed in the ailing cattle might have worsened the anoxia. Administration of antibiotics like penicillin, aminoglycosides, and tetracyclines further worsen the neuronal paralysis by increasing the availability of botulinum neurotoxin. Cattle in early botulism have fair chances of recovery with the modified therapy.

Keywords: botulism, cattle, neurotoxin, paralysis, therapy.

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