| 
              
              
              Open Access  
 
              
              
              
              Research 
              
              
(Published 
				online: 22-08-2016)  
              14. 
				
				
				Low-level laser therapy: Case-control 
				study in dogs with sterile pyogranulomatous pododermatitis -
				
				
				Roberta Perego, D. Proverbio, A. Zuccaro and E. Spada 
              
              Veterinary World, 9(8): 882-887   
              
   
                
                
doi: 
              
				
				10.14202/vetworld.2016.882-887 
                
				  
				
				Roberta Perego: 
				
				Department of Veterinary Sciences for Health, Animal Production 
				and Food Safety (VESPA), University of Milan, Via Celoria 10, 
				20133 Milano, Italy; roberta.perego@unimi.it 
				
				D. Proverbio: 
				
				Department of Veterinary Sciences for Health, Animal Production 
				and Food Safety (VESPA), University of Milan, Via Celoria 10, 
				20133 Milano, Italy; daniela.proverbio@unimi.it 
				
				A. Zuccaro: 
				
				Department of Veterinary Sciences for Health, Animal Production 
				and Food Safety (VESPA), University of Milan, Via Celoria 10, 
				20133 Milano, Italy; alice.zuccaro@fastwebnet.it 
				
				E. Spada: 
				
				Department of Veterinary Sciences for Health, Animal Production 
				and Food Safety (VESPA), University of Milan, Via Celoria 10, 
				20133 Milano, Italy; eva.spada@unimi.it   
				
				Received: 28-12-2015, Accepted: 19-07-2016, Published online: 
				22-08-2016   
				
              	
              	Corresponding author: 
              	
				
				Roberta Perego, e-mail: roberta.perego@unimi.it 
 
              Citation: Perego R, Proverbio D, Zuccaro A, Spada E (2016) Low-level laser 
				therapy: Case-control study in dogs with sterile 
				pyogranulomatous pododermatitis, 
				
				Veterinary World, 9(8): 
				882-887. 
 
              
				Abstract 
 
				
				
				Aim: 
				
				Low-level laser therapy (LLLT) is a therapeutic 
				photobiostimulation with properties in reducing swelling, 
				inflammation, and promoting tissue healing. The objective of 
				this pilot study was to evaluate LLLT in sterile 
				pyogranulomatous pododermatitis in five dogs. 
				
				
				Materials and Methods: 
				
				In each dog, one lesion was designated as the control (treated 
				with a 0.0584% hydrocortisone aceponate spray), and one or more 
				other lesions were treated with a gallium aluminum 
				arsenide-laser, daily for 5 days. Lesions were scored before 
				treatment (D0), at the end (D4), 16 days after the last laser 
				treatment (D20), and after 2 months (D65). 
				
				
				Results: 
				
				Comparing the treated lesion group with the control lesion 
				group, the clinical score was similar at D0, whereas there was a 
				statistically significant difference at D4 and D20; in the 
				treated group over time, there was a statistically significant 
				improvement between D0, D4, and D20. Lesion recurrence was 
				absent in more than 50% of the treated lesions at D65. No 
				adverse reactions were reported. 
				
				
				Conclusion: 
				
				Given the positive results of this first clinical study, it 
				would be interesting to extend the study to confirm the validity 
				of this type of therapy in sterile pyogranulomatous 
				pododermatitis in the dog. 
				
				Keywords: 
				
				case-control study, dog, low-level laser therapy, skin, sterile 
				pyogranulomatous pododermatitis. 
 
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