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Research (Published online: 29-03-2016)

20. Caprine leptospirosis: Hematobiochemical and urinalyses studies - Priti Dilipsinh Vihol, Jignesh M. Patel, Jatin H. Patel, Mahesh C. Prasad, Irsadullakhan H. Kalyani and Balkrushna P. Brahmkshtri

Veterinary World, 9(3): 337-341



   doi: 10.14202/vetworld.2016.337-341



Priti Dilipsinh Vihol: Department of Veterinary Pathology, Vanbandhu College of Veterinary Science and Animal Husbandry, Navsari Agricultural University, Navsari - 396 450, Gujarat, India;

Jignesh M. Patel: Department of Veterinary Pathology, Vanbandhu College of Veterinary Science and Animal Husbandry, Navsari Agricultural University, Navsari - 396 450, Gujarat, India;

Jatin H. Patel: Department of Veterinary Pharmacology and Toxicology, Vanbandhu College of Veterinary Science and Animal Husbandry, Navsari Agricultural University, Navsari - 396 450, Gujarat, India;

Mahesh C. Prasad: Department of Veterinary Pathology, Vanbandhu College of Veterinary Science and Animal Husbandry, Navsari Agricultural University, Navsari - 396 450, Gujarat, India;

Irsadullakhan H. Kalyani: Department of Veterinary Microbiology, Vanbandhu College of Veterinary Science and Animal Husbandry, Navsari Agricultural University, Navsari - 396 450, Gujarat, India;

Balkrushna P. Brahmkshtri: Department of Animal Genetics and Breeding, Vanbandhu College of Veterinary Science and Animal Husbandry, Navsari Agricultural University, Navsari - 396 450, Gujarat, India;


Received: 13-07-2015, Revised: 08-02-2016, Accepted: 18-02-2016, Published online: 29-03-2016


Corresponding author: Priti Dilipsinh Vihol, e-mail:

Citation: Vihol PD, Patel JM, Patel JH, Prasad MC, Kalyani IH, Brahmkshtri BP (2016) Caprine leptospirosis: Hematobiochemical and urinalyses studies, Veterinary World, 9(3): 337-341.

Aim: The present study was designed to evaluate clinicopathological alterations in naturally occurring leptospirosis in goats of South Gujarat region, Gujarat.

Materials and Methods: A total 459 blood/serum and 292 urine samples were collected from different districts of South Gujarat region, India. Blood/serum and urine samples were subjected to hematobiochemical analyses and urinalyses. The serum samples were screened for anti-leptospiral antibodies using the microscopic agglutination test (MAT). On the bases of presence or absence of anti-leptospiral antibodies in serum, seropositive and seronegative groups were made. The results were analyzed using standard statistical methods to know pathological changes in the disease.

Results: In MAT, out of 459, 116 goats were seropositive, and 343 were seronegative. In hematobiochemical analyses, statistically significant (p<0.01) decrease in values of packed cell volume, hemoglobin (Hb) concentration, mean corpuscular Hb concentration and total protein and increased activity/level of alanine aminotransferase, aspartate aminotransferase and total bilirubin between seropositive and seronegative goats were noted. Urinalyses did not reveal any specific changes. In the dark field microscopy, urine samples were found to be negative for leptospires.

Conclusion: Hematobiochemical changes noted in seropositive goats were indicative of hepatic damage, and this knowledge would aid in the therapeutic management of the disease.

Keywords: goats, hematobiochemical, leptospirosis, urinalysis.

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