Open Access
Research
(Published
online: 29-03-2016)
20.
Caprine leptospirosis: Hematobiochemical
and urinalyses studies -
Priti Dilipsinh Vihol, Jignesh M. Patel, Jatin H. Patel, Mahesh
C. Prasad, Irsadullakhan H. Kalyani and Balkrushna P.
Brahmkshtri
Veterinary World, 9(3): 337-341
doi:
10.14202/vetworld.2016.337-341
Priti Dilipsinh Vihol:
Department of Veterinary Pathology, Vanbandhu College of
Veterinary Science and Animal Husbandry, Navsari Agricultural
University, Navsari - 396 450, Gujarat, India; drpritivet@gmail.com
Jignesh M. Patel:
Department of Veterinary Pathology, Vanbandhu College of
Veterinary Science and Animal Husbandry, Navsari Agricultural
University, Navsari - 396 450, Gujarat, India; dr.jams@rediffmail.com
Jatin H. Patel:
Department of Veterinary Pharmacology and Toxicology, Vanbandhu
College of Veterinary Science and Animal Husbandry, Navsari
Agricultural University, Navsari - 396 450, Gujarat, India;
drjatinvet@yahoo.co.in
Mahesh C. Prasad:
Department of Veterinary Pathology, Vanbandhu College of
Veterinary Science and Animal Husbandry, Navsari Agricultural
University, Navsari - 396 450, Gujarat, India; drmcprasad1938@gmail.com
Irsadullakhan H. Kalyani:
Department of Veterinary Microbiology, Vanbandhu College of
Veterinary Science and Animal Husbandry, Navsari Agricultural
University, Navsari - 396 450, Gujarat, India; ihkvet@yahoo.com
Balkrushna P. Brahmkshtri:
Department of Animal Genetics and Breeding, Vanbandhu College of
Veterinary Science and Animal Husbandry, Navsari Agricultural
University, Navsari - 396 450, Gujarat, India; bpbkhatri@gmail.com
Received: 13-07-2015, Revised: 08-02-2016, Accepted: 18-02-2016,
Published online: 29-03-2016
Corresponding author:
Priti Dilipsinh Vihol, e-mail: drpritivet@gmail.com
Citation:
Vihol PD, Patel JM, Patel JH, Prasad MC, Kalyani IH, Brahmkshtri
BP (2016) Caprine leptospirosis: Hematobiochemical and
urinalyses studies,
Veterinary World,
9(3):
337-341.
Abstract
Aim:
The present study was designed to evaluate clinicopathological
alterations in naturally occurring leptospirosis in goats of
South Gujarat region, Gujarat.
Materials and Methods:
A total 459 blood/serum and 292 urine samples were collected
from different districts of South Gujarat region, India.
Blood/serum and urine samples were subjected to
hematobiochemical analyses and urinalyses. The serum samples
were screened for anti-leptospiral antibodies using the
microscopic agglutination test (MAT). On the bases of presence
or absence of anti-leptospiral antibodies in serum, seropositive
and seronegative groups were made. The results were analyzed
using standard statistical methods to know pathological changes
in the disease.
Results:
In MAT, out of 459, 116 goats were seropositive, and 343 were
seronegative. In hematobiochemical analyses, statistically
significant (p<0.01) decrease in values of packed cell volume,
hemoglobin (Hb) concentration, mean corpuscular Hb concentration
and total protein and increased activity/level of alanine
aminotransferase, aspartate aminotransferase and total bilirubin
between seropositive and seronegative goats were noted.
Urinalyses did not reveal any specific changes. In the dark
field microscopy, urine samples were found to be negative for
leptospires.
Conclusion:
Hematobiochemical changes noted in seropositive goats were
indicative of hepatic damage, and this knowledge would aid in
the therapeutic management of the disease.
Keywords:
goats, hematobiochemical, leptospirosis, urinalysis.
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