Open Access
Research
(Published
online: 14-11-2016)
13.
Prevalence of ketosis in dairy cows in milk
shed areas of Odisha state, India -
Sangram Biswal, Dhruba Charan Nayak and Kautuk Kumar Sardar
Veterinary World, 9(11): 1242-1247
doi:
10.14202/vetworld.2016.1242-1247
Sangram Biswal:
Department of Veterinary Medicine, College of Veterinary Science
and Animal Husbandry, Orissa University of Agriculture and
Technology, Bhubaneswar, Odisha, India; drsangrambiswal@gmail.com
Dhruba Charan Nayak:
Department of Veterinary Medicine, College of Veterinary Science
and Animal Husbandry, Orissa University of Agriculture and
Technology, Bhubaneswar, Odisha, India; dcnayak01@rediffmail.com
Kautuk Kumar Sardar:
Department of Pharmacology and Toxicology, College of Veterinary
Science and Animal Husbandry, Orissa University of Agriculture and
Technology, Bhubaneswar, Odisha, India; kksardar@gmail.com
Received: 10-07-2016, Accepted: 03-10-2016, Published online:
14-11-2016
Corresponding author:
Sangram Biswal, e-mail: drsangrambiswal@gmail.com
Citation:
Biswal S, Nayak DC, Sardar KK (2016) Prevalence of ketosis in
dairy cows in milk shed areas of Odisha state, India,
Veterinary World, 9(11):
1242-1247.
Abstract
Aim:
The present study was conducted to ascertain the prevalence of
ketosis in dairy cows in dairy herds, milksheds, and mixed
population of milk cows selected randomly in milkshed areas of
Odisha state, India.
Materials and Methods:
The investigation was conducted in 280 private dairy herds with
variable herd size of 10-15 cows comprising crossbred Jersey cows
(CBJ), crossbred Holstein Friesian (CHF) cows, and indigenous
local breeds. The analysis of urine (Rothera’s test), milk (Ross
test), and blood samples of 2760 test cows were conducted through
qualitative assessment by Rothera’s test and Ross test,
respectively, for the presence of ketone bodies to screen the
ketotic animals. Cut-points have been decided based on β-hydroxybutyric
acid level (≥1.2-1.4 mmol/L) in milk.
Results:
We noted positive cases of ketosis with a prevalence rate of 36.7%
(1014/2760) entailing 27.2% in clinical ketosis and 9.6% in
subclinical ketosis. The breed wise incident rate was recorded to
be the highest (38.0%) in CBJs. The age-wise prevalence rate was
found to be the highest (40.8%) in the age group of 5.5-6.5 years.
The season wise prevalence rate in 5th calver was recorded to be
the highest (38.6%) in summer season as compared to other seasons.
The prevalence of ketosis was observed to be the highest at 56.7%
on the first stage of lactation at the 1st month after 2 weeks.
The incidence rates for clinical and subclinical ketosis were
found to be 25.2%; 12.2%, 26.6%; 11.2% and 30.3%; 2.9% in CBJ, CHF
and indigenous cows, respectively. The breed wise overall
prevalence rate was recorded to be 38.0% in CBJ, 37.8% in CHF, and
33.2% in indigenous cows.
Conclusion:
Ketosis and subclinical ketosis is highly prevalent metabolic
disorder and has severe effect on the production status of
affected animal and needs to be prevented, rather than treated, by
maintaining cows in good and healthy conditions. We have attempted
to give great attention for diagnosis, management, and control of
this disease during risk stage to prevent economic loss sustained
by the dairy farmers of Eastern India.
Keywords:
age, breed, dairy, ketosis, lactation, milk cows, prevalence.
References
1. Holmes, J.R. (1950) Observations on the incidence of
subclinical ketosis in a dairy herd. Br. Vet. J., 106:
365-377.
PMid:14777919 |
|
|
|
2. Radostits, O.M., Gay, C.C., Hinchcliff, K. and Constable,
P.D. (2010) Veterinary Medicine: A Textbook of the Diseases of
Cattle, Horses, Sheep, Pigs and Goats. 10th ed. Saunders
Elsevier, Philadelphia, PA. |
|
|
3. Andersson, L. (1988) Subclinical ketosis in dairy cows.
Vet. Clin. North Am. Food Anim. Pract., 4: 233-251.
https:/doi.org/10.1016/S0749-0720(15)31046-X |
|
|
4. Duffield, T. (2000) Subclinical ketosis in lactating dairy
cattle. Vet. Clin. North Am. Food Anim. Pract., 16: 231-253.
https:/doi.org/10.1016/S0749-0720(15)30103-1 |
|
|
5. Ospina, P.A., Nydam, D.V., Stokol, T. and Overton, T.R.
(2010a) Associations of elevated nonesterified fatty acids and
β-hydroxybutyrate concentrations with early lactation
reproductive performance and milk production in transition
dairy cattle in the Northeastern United States. J. Dairy Sci.,
93: 1596-1603.
https:/doi.org/10.3168/jds.2009-2852
PMid:20338437 |
|
|
6. Chapinal, N., Carson, M.E., LeBlanc, S.J., Leslie, K.E.,
Godden, S., Capel, M., Santos, J.E., Overton, M.W. and
Duffield, T.F. (2012) The association of serum metabolites in
the transition period with milk production and early-lactation
reproductive performance. J. Dairy Sci., 95: 1301-1309.
https:/doi.org/10.3168/jds.2011-4724
PMid:22365212 |
|
|
7. Roberts, T., Chapinal, N., LeBlanc, S.J., Kelton, D.F.,
Dubuc, J. and Duffield, T.F. (2012) Metabolic parameters in
transition cows as indicators for early-lactation culling
risk. J. Dairy Sci., 95: 3057-3063.
https:/doi.org/10.3168/jds.2011-4937
PMid:22612941 |
|
|
8. Kumar, A., Sindhu, N., Kumar, P., Kumar, T., Charaya, G.,
Surbhi, Jain, V.K. and Sridhar. (2015) Incidence and clinical
vital parameters in primary ketosis of murrah buffaloes. Vet.
World, 8(9): 1083-1087.
https:/doi.org/10.14202/vetworld.2015.1083-1087
PMid:27047203 PMCid:PMC4774777 |
|
|
9. McKay, S. (2012) Subclinical ketosis: Frequent and an
expensive problem. Tijdschr. Diergeneeskd., 137: 686-687, 689.
PMid:23101340 |
|
|
|
10. Nayak, L.K. (1999) Studies on Comparative Efficacy of
Different Therapeutic Regimen Against Bovine Ketosis. M.V.Sc.
Thesis Submitted to the Orissa University of Agriculture and
Technology, Bhubaneswar. |
|
|
|
11. Mohanty, P.K. (1998) Studies of Bovine Ketosis and its
Management. M.V.Sc. Thesis Submitted to the Orissa University
of Agriculture and Technology, Bhubaneswar. |
|
|
|
12. Panda, A. (2003) Studies on Some Aspects of
Clinical-biochemical Changes of Bovine Ketosis and its
Therapy. M.V.Sc. Thesis Submitted to the Orissa University of
Agriculture and Technology, Bhubaneswar. |
|
|
|
13. Willadsen, C.M., Quesel, J. and Nilleberg, P. (1993)
Ketosis in dairy herds: II. Epidemiological investigations.
Dansk Veterinaertidsskrift, 76: 275-280. |
|
|
|
14. Kegl, T. (1990) Investigation and control of ketonuria in
a Holstein Friesian dairy herd. Magy. Allatorvosok Iapja., 45:
393-398. |
|
|
|
15. Ziauddin, K.S., Muralidharan, K., Seshadri, S.J., Hussain,
P.M. and Sreenivasaiah, P.V. (1992) Incidence of ketonuria
among local and crossbred cows. A five year observation.
Indian Vet. Med. J., 16: 310-312. |
|
|
16. Lean, I.J., Bruss, M.L., Troutt, H.F., Galland, J.C.,
Farver, T.B., Rostami, J., Holmberg, C.A. and Weaver, L.D.
(1994) Bovine ketosis and somatotropin: Risk factors for
ketosis and effects of ketosis on health and production. Res.
Vet. Sci., 57: 200-209.
https:/doi.org/10.1016/0034-5288(94)90058-2 |
|
|
|
17. Venkateshwarlu, K. (1996) Investigation into the
Diagnosis, Pathogenesis, Biochemical Changes and Treatment of
Subclinical Ketosis in Cross Bred Cows. Ph.D. Thesis Submitted
to Andhra Pradesh Agricultural University, Hyderabad. |
|
|
|
18. Reddy, J.S., Syamasunder, N. and Choudhuri, P.C. (1986)
Subclinical ketosis in crossbred cattle in an organized dairy
herd. J. Res., 14: 170-172. |
|
|
|
19. Bhuin, S. and Chakraberti, A. (1993) A note on the
prevalence of ketosis in West Bengal. Indian Vet. J., 70:
582-583. |
|
|
|
20. Asrat, M., Tadesse, G.H., Gounder, R.V. and Nagappan, R.
(2013) Prevalence and treatment of ketosis in dairy cows in
and around Addis Ababa, Ethiopia. Br. J. Dairy Sci., 3(3):
26-30. |
|
|
|
21. Schaffer, M. and Bethe, W. (1976) Occurrence of ketosis in
our dairy herd. Monat. Vet. Med., 31: 505-508. |
|
|
|
22. Lopelfernandez, J.A. (1993) Bovine ketosis: An important
disease on small holdings. Adv. Aliment. Mejora Anim., 33:
127-130. |
|
|
23. Berge, A.C. and Vertenten, G. (2014) A field study to
determine the prevalence, dairy herd management systems, and
fresh cow clinical conditions associated with ketosis in
Western European dairy herds. J. Dairy Sci., 97: 2145-2154.
https:/doi.org/10.3168/jds.2013-7163
PMid:24534510 |
|
|
24. Santschi, D.E., Lefebvre, D.M., Cue, R.I., Girard, C.L.
and Pellerin, D. (2011) Incidence of metabolic disorders and
reproductive performance following a short (35-d) or
conventional (60-d) dry period management in commercial
Holstein herds. J. Dairy Sci., 94(7): 3322-3330.
https:/doi.org/10.3168/jds.2010-3595
PMid:21700018 |
|
|
25. Dash, S., Chakravarty, A.K., Singh, A., Upadhyay, A.,
Singh, M. and Yousuf, S. (2016) Effect of heat stress on
reproductive performances of dairy cattle and buffaloes: A
review. Vet. World, 9(3): 235-244.
https:/doi.org/10.14202/vetworld.2016.235-244
PMid:27057105 PMCid:PMC4823282 |
|
|
|
26. Zhang, Z., Liu, G., Wang, H., Li, X. and Wang, Z. (2012)
Detection of subclinical ketosis in dairy cows. Pak. Vet. J.,
32(2): 156-160. |
|
|
|
27. Thirunavukkarasu, M., Kathiravan, G., Kalaikannan, A. and
Jebarani, W. (2010) Prevalence of ketosis in dairy farms – A
survey in Tamil Nadu. Tamilnadu J. Vet. Anim. Sci., 6(4):
193-195. |
|
|
28. Schultz, L.H. (1968) Ketosis in dairy cattle. J. Dairy Sci.,
51: 1133-1140.
https:/doi.org/10.3168/jds.S0022-0302(68)87141-3 |
|
|
29. Duffield, T., Lissemore, K., McBride, B. and Leslie, K.
(2009) Impact of hyperketonemia in early lactation dairy cows
on health and production. J. Dairy Sci., 92: 571-580.
https:/doi.org/10.3168/jds.2008-1507
PMid:19164667 |
|
|
30. McArt, J.A., Nydam, D.V. and Oetzel, G.R. (2012b)
Epidemiology of subclinical ketosis in early lactation dairy
cattle. J. Dairy Sci., 95: 5056-5066.
https:/doi.org/10.3168/jds.2012-5443
PMid:22916909 |
|
|
|
31. Oetzel, G. (2013) Understanding the Impact of Subclinical
Ketosis. 24th Ruminant Nutrition Symposium. Available from:
http://www.dairy.ifas.ufl.edu /rns. Last accessed on
27/05/2016. |
|
|
|
32. Singh, B. and Kasaralikar, V.R. (1990) Biochemistry and
treatment of clinical ketosis in buffaloes. Indian Vet. J.,
67: 163-165. |
|
|
|
33. Duncan, C.W., Huffman, C.F. and Tobin, H.A. (1939) A
chemical study of ketosis in dairy herd. J. Am. Vet. Med.
Assoc., 95: 690-700. |
|
|
34. Emery, R.S., Bell, J.W. and Thomas, J.W. (1968) Benefits
derived from routine testing for milk ketone. J. Dairy Sci.,
51: 867-874.
https:/doi.org/10.3168/jds.S0022-0302(68)87095-X |
|
|
|
35. Anantwar, L.G. and Singh, B. (1993) Epidemiology, clinico-pathology
and treatment of clinical ketosis in buffaloes (Bubalus
bubalis). Indian Vet. J., 70: 152-156. |
|
|
36. Haghighat-Jahromi, M. and Nahid, S. (2011) Incidence of
subclinical ketosis in dairy cows in Fars province of Iran and
reproductive performance in early lactation period. Asian J.
Anim. Sci., 5(2): 158-161.
https:/doi.org/10.3923/ajas.2011.158.161 |
|
