Live vaccines against bacterial fish diseases: A review

Vet World Vol.12 November-2019 Article-17

Review Article

Veterinary World, 12(11): 1806-1815

https://doi.org/10.14202/vetworld.2019.1806-1815

Aslizah Mohd-Aris^1,2, Mohd Hafiz Ngoo Muhamad-Sofie², Mohd Zamri-Saad^2,3, Hassan Mohd Daud^2,4, and Md. Yasin Ina-Salwany^2,5

1. Department of Biology, School of Biology, Faculty of Applied Sciences, Universiti Teknologi MARA, Cawangan Negeri Sembilan, Kampus Kuala Pilah, Malaysia.
2. Laboratory of Marine Biotechnology, Institute of Bioscience, Universiti Putra Malaysia, Serdang, Malaysia.
3. Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Serdang, Malaysia.
4. Department of Veterinary Clinical Studies, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Serdang, Malaysia.
5. Department of Aquaculture, Faculty of Agriculture, Universiti Putra Malaysia, Serdang, Malaysia.

Background and Aim: Fish diseases are often caused either by bacteria, viruses, fungi, parasites, or a combination of these pathogens. Of these, bacterial fish diseases are considered to be a major problem in the aquaculture industry. Hence, the prevention of such diseases by proper vaccination is one of the integral strategies in fish health management, aimed at reducing the fish mortality rate in the aquaculture farms. Vaccination offers an effective yet low-cost solution to combat the risk of disease in fish farming. An appropriate vaccination regime to prevent bacterial diseases offers a solution against the harmful effects of antibiotic applications. This review discusses the role of live-attenuated vaccine in controlling bacterial diseases and the development of such vaccines and their vaccination strategy. The current achievements and potential applications of live-attenuated and combined vaccines are also highlighted. Vaccine development is concluded to be a demanding process, as it must satisfy the requirements of the aquaculture industry.

Keywords: aquaculture, attenuated vaccines, bacterial fish diseases, vaccination.

How to cite this article: Mohd-Aris A, Muhamad-Sofie MHN, Zamri-Saad M, Daud HM, Ina-Salwany MY (2019) Live vaccines against bacterial fish diseases: A review, Veterinary World, 12(11): 1806-1815.

Received: 29-07-2019 Accepted: 11-10-2019 Published online: 21-11-2019

Corresponding author: Aslizah Mohd-Aris E-mail: aslizah@uitm.edu.my

DOI: 10.14202/vetworld.2019.1806-1815

Copyright: Mohd-Aris, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.