Vet World   Vol.13   June-2020  Article-22

Review Article

Veterinary World, 13(6): 1174-1181

https://doi.org/10.14202/vetworld.2020.1174-1181

Dermatophytosis in companion animals: A review

Alsi Dara Paryuni1, Soedarmanto Indarjulianto2, and Sitarina Widyarini1
1. Department of Pathology, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.
2. Department of Internal Medicine, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.

Background and Aim: Dermatophytosis, a zoonotic disease, is caused by fungi of three main genera, namely, Micropsorum, Trichophyton, and Epidermophyton. Specific lesions of dermatophyte infections are localized in the face, legs, and/or tail. Skin lesions in infected animals demonstrate localized alopecia, erythema, and crust, which are more commonly known as ringworm. Factors that affect dermatophytosis include the dermatophyte species; virulence factors of the agent; and the immune status, age, and sex of the host. High levels of cortisol and pro-inflammatory cytokines have also been reported to play an important role in dermatophyte infection. This review aims to explore and understand factors that affect dermatophyte infection with an emphasis on the prevalence, clinical signs, pathogenesis, immune response, and the roles of cortisol and cytokines in companion animals infected by a dermatophyte.

Keywords: clinical signs, cortisol, cytokine, dermatophytosis, immune response, pathogenesis.

How to cite this article: Paryuni AD, Indarjulianto S, Widyarini S (2020) Dermatophytosis in companion animals: A review, Veterinary World, 13(6): 1174-1181.

Received: 07-02-2020  Accepted: 29-04-2020     Published online: 22-06-2020

Corresponding author: Sitarina Widyarini   E-mail: sitarina@ugm.ac.id

DOI: 10.14202/vetworld.2020.1174-1181

Copyright: Paryuni, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.