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52 articles matching “animal model”

03
Review Article28 Apr 2026Vol. 19 · Issue 4

Neuroprotective potential of Mucuna pruriens in cerebral ischemia: Evidence from animal models and implications for translational neuropharmacology

Bukkambudhi Virupakshamurthy Murlimanju

This review summarizes the available evidence from animal model studies on the role of M. pruriens in the management of cerebral ischemia. The literature indicates that M. pruriens can reduce oxidative stress by enhancing antioxidant enzyme activities, includ…

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04
Systematic Review31 May 2025Vol. 18 · Issue 5

Histological response and blood glucose level in a diabetic animal model after the oral administration of Mucuna pruriens: A systematic review and meta-analysis

Tri Wahyu Pangestiningsih

This study systematically evaluated the dual impact of orally administered MP extract on histopathological changes and blood glucose levels in diabetic animal models through a systematic review and meta-analysis.

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05
Research Article19 Nov 2023Vol. 16 · Issue 11

Unraveling the relationship among inflammatory responses, oxidative damage, and host susceptibility to Opisthorchis viverrini infection: A comparative analysis in animal models

Sirikachorn Tangkawattana

This study aimed to explore the potential role of inflammation and RNS in causing DNA damage that may predispose susceptible hosts and non-susceptible animal models to cancer development in O. viverrini infection.

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06
Research Article24 Mar 2023Vol. 16 · Issue 3

Psychological dominant stressor modification to an animal model of depression with chronic unpredictable mild stress

Irwanto Irwanto

Therefore, this study aimed to create an animal model of depression, mainly focusing on a psychologically dominant stressor without food and water deprivation.

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07
Research Article14 Jul 2020Vol. 13 · Issue 7

Preliminary screening of the possible protective effect of Moroccan propolis against chromium-induced nephrotoxicity in animal model

Badiaa Lyoussi

The aim of the present study was to investigate the nephroprotective effect of bee propolis, as highly antioxidant natural product, in vivo using an animal model

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08
Research Article18 May 2022Vol. 15 · Issue 5

Potential use of Indonesian basil (Ocimum basilicum) maceration to increase estradiol and progesterone synthesis and secretion to improve prenatal growth of offspring using female albino rats as an animal model

Wasmen Manalu

This study aimed to evaluate the effect of Indonesian basil maceration on gonad development of mature female albino rats

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09
Research Article19 Jun 2019Vol. 12 · Issue 6

Diabetes sepsis on Wistar rat strain (Rattus norvegicus) induced by streptozotocin and bacteria Staphylococcus aureus

Dahliatul Qosimah

The study aimed to determine the method of using animal models of sepsis diabetes through a combination of streptozotocin and Staphylococcus aureus infection based on biological marker parameters

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10
Review Article14 Oct 2025Vol. 18 · Issue 10

Experimental models of epilepsy: A comprehensive review of mechanisms, translational relevance, and future directions

Nayanatara Arun Kumar

This review pro­vides a comprehensive framework to guide future research aimed at improving therapeutic strategies and bridging the gap between pre-clinical and clinical epilepsy research.

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11
Research Article12 May 2025Vol. 18 · Issue 5

A lung cancer mouse model system based on an inbred C3H strain: Ultrasound imaging, pathological analysis, and proteomic biomarker identification

Hevi Wihadmadyatami

This study aimed to develop and validate a novel lung cancer mouse model using the inbred C3H strain through intraperitoneal (I.P) injection of benzo(a)pyrene, offering insights into hematology, pathology, imaging, and proteomic biomarkers.

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13
Research Article27 Nov 2023Vol. 16 · Issue 11

Recent advances in the treatment of pain in endometriosis: A bibliometric analysis of experimental models

Rafael Abreu Lima

Therefore, this study aimed to systematically evaluate research trends and critical points in the field of endometriosis pain management using experimental models.

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15
Research Article17 Apr 2022Vol. 15 · Issue 4

Spontaneous expression of the gene of KI67 and P53 in cynomolgus monkeys infected with papillomavirus

Huda S. Darusman

This study aimed to investigate the messenger ribonucleic acid (mRNA) expression levels of KI67 and P53 genes, majorly known as biomarker oncogenesis of PV infection

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