Article history: Received: 14-09-2017, Accepted: 10-01-2018, Published online: 19-02-2018
Corresponding author: Dina Aboelsoued
E-mail: Dr.Dina.Aboelsoued@gmail.comCitation: Hegazi AG, Abdel Megeed KN, Hassan SE, Abdelaziz MM, Toaleb NI, El Shanawany EE, Aboelsoued D (2018) Comparative ovicidal activity of Moringa oleifera leaf extracts on Fasciola gigantica eggs, Veterinary World, 11(2): 215-220.
Background: Fasciolosis is an important zoonotic disease affecting the productive performance of farm animals in Egypt.
Aim: The aim of the present study was comparing the ovicidal effect of different extracts as an alcoholic (Methanolic and Ethanolic) and aqueous Moringa oleifera leaf extracts on Fasciola gigantica non-embryonated and developed eggs.
Materials and Methods: Tested concentrations of extracts ranged from 12.5 to 800 mg/ml. Nitroxynil was used as reference drug with a dose of 100 mg/ml.
Results: M. oleifera alcoholic and aqueous extracts showed a concentration-dependent ovicidal effect on F. gigantica non-embryonated and developed eggs. Based on LC50 values, water extract showed the highest ovicidal activity since it registered the lowest values of 2.6 mg/ml on non-embryonated eggs. Non-embryonated eggs were more susceptible to aqueous extract than developed eggs. On the other hand, the developed eggs were more susceptible to ethanolic extract than non-embryonated eggs even the lowest LC50 (12.38 mg/ml).
Conclusion: M. oleifera leaf extracts especially aqueous extract could be a promising step in the field of controlling fascioliasis. Further, in vivo studies are needed to enlighten the therapeutic potential of M. oleifera extracts in treating F. gigantica infection.
Keywords: Fasciola gigantica, leaf extract, Moringa oleifera, nitroxynil, ovicidal activity.
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